Description
The recent introduction of comprehensive, brain-wide gene expression atlases such as the Allen Human Brain Atlas has opened new opportunities for understanding how spatial variations on the molecular transcriptomic scale relate to the macroscopic neuroimaging phenotypes. This unprecedented capacity to link molecular pathways to macroscale brain organization has given rise to the emergent field of imaging transcriptomics. Imaging transcriptomics is concerned with the identification of spatial correlations between gene expression patterns and some properties of brain structure or function, as measured by neuroimaging . The main goal of this approach is to identify genes with spatial profiles of regional expression that track anatomical variations in a certain neuroimaging biomarker.In this workshop, we will bring together experts from around the globe to discuss current advances in the methods and applications of Imaging Transcriptomics to the study of the brain. We will discuss practical aspects of the implementation of these analyses and present easy-to-use pipelines that the non-expert can use to perform these analyses.
Speakers
Prof. Mattia Veronese (University of Padova, Italy)
Dr. Jakob Seidlitz ( Lifespan Brain Institute of Children’s Hospital of Philadelphia and University of Pennsylvania, USA)
Dr. Bratislav Misic (Montreal Neurological Institute, Canada)
Prof. Jason Lerch (University of Oxford, UK)
Mr. Alessio Giacomel (IoPPN, KCL, UK) - Demo on the "Imaging Transcriptomics toolbox"
Chair: Dr. Daniel Martins, MD PhD, IoPPN, King's College London, UK
This event is a joint venture between the Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London and the NIHR Maudsley BRC, South London and Maudsley NHS Trust (Neuroimaging Theme).
| Period | 5 Mar 2021 |
|---|---|
| Held at | Neuroimaging |
| Degree of Recognition | International |
Keywords
- imaging transcriptomics
- brain
- allen brain atlas
- multimodal
- Open source research methodology