Research output per year
Research output per year
Search results
-
2016
Heat shock protein-based therapy as a potential candidate for treating the sphingolipidoses
Kirkegaard, T., Gray, J., Priestman, D. A., Wallom, K. L., Atkins, J., Olsen, O. D., Klein, A., Drndarski, S., Petersen, N. H. T., Ingemann, L., Smith, D. A., Morris, L., Bornæs, C., Jørgensen, S. H., Williams, I., Hinsby, A., Arenz, C., Begley, D., Jäättelä, M. & Platt, F. M., 7 Sept 2016, In: Science Translational Medicine. 8, 355, 355ra118.Research output: Contribution to journal › Article › peer-review
122 Citations (Scopus) -
2014
Intrathecal delivery of protein therapeutics to the brain: A critical reassessment
Calias, P., Banks, W. A., Begley, D., Scarpa, M. & Dickson, P., 2014, In: Pharmacology and Therapeutics. 144, 2, p. 114-122 9 p.Research output: Contribution to journal › Article › peer-review
Open Access122 Citations (Scopus) -
2013
Cyclodextrin alleviates neuronal storage of cholesterol in Niemann-Pick C disease without evidence of detectable blood-brain barrier permeability
Pontikis, C. C., Davidson, C. D., Walkley, S. U., Platt, F. M. & Begley, D. J., May 2013, In: Journal of Inherited Metabolic Disease. 36, 3, p. 491-498 8 p.Research output: Contribution to journal › Article › peer-review
72 Citations (Scopus) -
2010
Human serum albumin nanoparticles modified with apolipoprotein A-I cross the blood-brain barrier and enter the rodent brain
Zensi, A., Begley, D., Pontikis, C., Legros, C., Mihoreanu, L., Buechel, C. & Kreuter, J., Dec 2010, In: Journal of Drug Targeting. 18, 10, p. 842-848 7 p.Research output: Contribution to journal › Article › peer-review
112 Citations (Scopus) -
Structure and function of the blood-brain barrier
Abbott, N. J., Patabendige, A. A. K., Dolman, D. E. M., Yusof, S. R. & Begley, D. J., Jan 2010, In: Neurobiology of Disease. 37, 1, p. 13 - 25 13 p.Research output: Contribution to journal › Literature review › peer-review
3795 Citations (Scopus) -
2004
Flavonoid permeability across an in situ model of the blood-brain barrier
Youdim, K. A., Qaiser, M. Z., Begley, D. J., Rice-Evans, C. A. & Abbott, N. J., 1 Mar 2004, In: Free Radical Biology and Medicine. 36, 5, p. 592 - 604 13 p.Research output: Contribution to journal › Article › peer-review
548 Citations (Scopus) -
2003
Direct evidence that polysorbate-80-coated poly( butylcyanoacrylate) nanoparticles deliver drugs to the CNS via specific mechanisms requiring prior binding of drug to the nanoparticles
Kreuter, J., Ramge, P., Petrov, V., Hamm, S., Gelperina, S. E., Engelhardt, B., Alyautdin, R., von Briesen, H. & Begley, D. J., 1 Mar 2003, In: Pharmaceutical Research. 20, 3, p. 409 - 416 8 p.Research output: Contribution to journal › Article › peer-review
470 Citations (Scopus)