Research output per year
Research output per year
- 23 results
Search results
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2022
Lipids in Liver Failure Syndromes: A Focus on Eicosanoids, Specialized Pro-Resolving Lipid Mediators and Lysophospholipids
Artru, F., McPhail, M. J. W., Triantafyllou, E. & Trovato, F. M., 31 Mar 2022, In: Frontiers in Immunology. 13, 867261.Research output: Contribution to journal › Review article › peer-review
Open Access14 Citations (Scopus) -
2021
Dysregulation of the Lysophosphatidylcholine/Autotaxin/Lysophosphatidic Acid Axis in Acute-on-Chronic Liver Failure Is Associated With Mortality and Systemic Inflammation by Lysophosphatidic Acid–Dependent Monocyte Activation
Trovato, F. M., Zia, R., Napoli, S., Wolfer, K., Huang, X., Morgan, P. E., Husbyn, H., Elgosbi, M., Lucangeli, M., Miquel, R., Wilson, I., Heaton, N. D., Heneghan, M. A., Auzinger, G., Antoniades, C. G., Wendon, J. A., Patel, V. C., Coen, M., Triantafyllou, E. & McPhail, M. J., Aug 2021, In: Hepatology. 74, 2, p. 907-925 19 p.Research output: Contribution to journal › Article › peer-review
Open Access31 Citations (Scopus) -
Low baseline cortisol but not delta cortisol relates to 28-day transplant-free survival in acute liver failure syndromes
Roth, S., Flint, E., Ghataore, L., Patel, V. C., Singanayagam, A., Vincent, R. P., Triantafyllou, E., Ma, Y., Bernal, W., Auzinger, G., Heneghan, M., McPhail, M., Antoniades, C., Christ-Crain, M., Taylor, D. R., Wendon, J. & Bernsmeier, C., Jul 2021, In: Journal of Hepatology. 75, p. S306-S306Research output: Contribution to journal › Meeting Abstract › peer-review
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OSTEOPONTIN, MACROPHAGE MANNOSE RECEPTOR AND SOLUBLE PD-L1 ARE UPREGULATED MACROPHAGE ACTIVATION MARKERS IN PATIENTS WITH ACUTE LIVER FAILURE
Cavazza, A., Huang, X., Triantafyllou, E., Ma, Y., Antoniades, C. G., Lee, W. M., McPhail, M. J. & Karvellas, C. J., Oct 2021, In: Hepatology. 74, p. 164A-165AResearch output: Contribution to journal › Meeting Abstract › peer-review
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PD-L1 expression of monocytes relates to severity, infection and mortality in acute-on-chronic liver failure
Triantafyllou, E., Trovato, F., Husbyn, H., Huang, X., Mukherjee, S., Bernsmeier, C., Goldin, R. D., Wendon, J., Possamai, L., Khamri, W., Thursz, M. & McPhail, M. J. W., Jul 2021, In: Journal of Hepatology. 75, p. S208-S208Research output: Contribution to journal › Meeting Abstract › peer-review
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Suppressor CD4+T cells expressing HLA-G are expanded in the peripheral blood from patients with acute decompensation of cirrhosis
Khamri, W., Gudd, C., Liu, T., Nathwani, R., Krasniqi, M., Azam, S., Barbera, T., Trovato, F. M., Possamai, L., Triantafyllou, E., Seoane, R. C., Lebosse, F., Singanayagam, A., Kumar, N., Bernsmeier, C., Mukherjee, S., McPhail, M., Weston, C. J., Antoniades, C. G. & Thursz, M. R., 3 Aug 2021, (E-pub ahead of print) In: Gut. 324071.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus) -
2019
Autotaxin mediates lipid dysregulation in acute-on-chronic liver failure, promoting persistence of systemic inflammation via lysophosphatidic acid-mediated monocyte activation
McPhail, M. J. W., Trovato, F., Triantafyllou, E., Zia, R., Wolfer, K., Huang, X., Rabinowich, L., Patel, V. C., Holmes, E., Heaton, N., Heneghan, M., Bernal, W., Auzinger, G., Coen, M., Wendon, J. & Antoniades, H., Apr 2019, In: Journal of Hepatology. 70, p. E91-E92Research output: Contribution to journal › Meeting Abstract › peer-review
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Immunometabolic profiling of ascites from patients with acute-on-chronic liver failure reveals increased MerTK plus immunosuppressive myeloid cells and cell death markers with preferential lipid metabolism compared to cirrhosis without organ failure
Singanayagam, A., Erminelli, D., Triantafyllou, E., Bernsmeier, C., Tunc, E., Krasniqi, M., Patel, V., Lebosse, F., Nathwani, R., Atkinson, A., Dhar, A., Heneghan, M., Auzinger, G., Khamri, W., Adams, D., Wendon, J., Thursz, M., McPhail, M. J. W. & Antoniades, H., Apr 2019, In: Journal of Hepatology. 70, p. E183-E183Research output: Contribution to journal › Meeting Abstract › peer-review
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PD-1+monocytes and macrophages contribute to impaired microbial clearance following acute liver failure
Triantafyllou, E., Gudd, C., Nathwani, R., Trovato, F., Possamai, L., Morrison, R., Bernsmeier, C., Patel, V., Khamri, W., Goldin, R., Wendon, J., McPhail, M., Woollard, K., Thursz, M. & Antoniades, C., Apr 2019, In: Journal of Hepatology. 70, p. E430-E431Research output: Contribution to journal › Meeting Abstract › peer-review
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2018
CD14+CD15-HLA-DR- myeloid-derived suppressor cells impair antimicrobial responses in patients with acute-on-chronic liver failure
Bernsmeier, C., Triantafyllou, E., Brenig, R., Lebosse, F. J., Singanayagam, A., Patel, V. C., Pop, O. T., Khamri, W., Nathwani, R., Tidswell, R., Weston, C. J., Adams, D. H., Thursz, M. R., Wendon, J. A. & Antoniades, C. G., Jun 2018, In: Gut. 67, 6, p. 1155-1167Research output: Contribution to journal › Article › peer-review
119 Citations (Scopus) -
MerTK expressing hepatic macrophages promote the resolution of inflammation in acute liver failure
Triantafyllou, E., Pop, O. T., Possamai, L. A., Wilhelm, A., Liaskou, E., Singanayagam, A., Bernsmeier, C., Khamri, W., Petts, G., Dargue, R., Davies, S. P., Tickle, J., Yuksel, M., Patel, V. C., Abeles, R. D., Stamataki, Z., Curbishley, S. M., Ma, Y., Wilson, I. D. & Coen, M. & 7 others, , Feb 2018, In: Gut. 67, 2, p. 333-347 15 p.Research output: Contribution to journal › Article › peer-review
Open Access159 Citations (Scopus) -
PLASMA S100A8/A9: A NOVEL MECHANISTIC BIOMARKER IN INNATE IMMUNE ACTIVATION IN ACUTE-ON-CHRONIC LIVER FAILURE
Singanayagam, A., Nathwani, R., Triantafyllou, E., Patel, V. C., Dhar, A., McPhail, M., Bernsmeier, C., Wendon, J. & Antoniades, C. G., Jun 2018, In: Gut. 67, p. A131-A132Research output: Contribution to journal › Meeting Abstract › peer-review
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The Role of Monocytes and Macrophages in Acute and Acute-on-Chronic Liver Failure
Triantafyllou, E., Woollard, K. J., McPhail, M. J. W., Antoniades, C. G. & Possamai, L. A., 14 Dec 2018, In: Frontiers in Immunology. 9Research output: Contribution to journal › Review article › peer-review
Open AccessFile204 Citations (Scopus)58 Downloads (Pure) -
2017
Increased Expression of CTLA4 by T Cells, Induced by B7 in Sera, Reduces Adaptive Immunity in Patients With Acute Liver Failure
Khamri, W., Abeles, R. D., Hou, T. Z., Anderson, A. E., El-Masry, A., Triantafyllou, E., Bernsmeier, C., Larsen, F. S., Singanayagam, A., Kudo, N., Possamai, L. A., Lebosse, F., Auzinger, G., Bernal, W., Willars, C., Weston, C. J., Lombardi, G., Wendon, J., Thursz, M. & Antoniades, C. G., 28 Mar 2017, (E-pub ahead of print) In: Gastroenterology. 153, p. 263-276 e8.Research output: Contribution to journal › Article › peer-review
Open AccessFile36 Citations (Scopus)306 Downloads (Pure) -
Role of expression of the tumour-associated macrophage receptor, MERTK, in hepatocellular carcinoma: Spring Meeting for Clinician Scientists in Training 2017
Mukherjee, S., Pop, O., Triantafyllou, E., Khamri, W., Curbishley, S., Thursz, M., Adams, D. & Antoniades, C., Feb 2017, In: Lancet. 389, Supplement 1, p. S72Research output: Contribution to journal › Poster abstract › peer-review
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2016
High-volume plasma exchange in patients with acute liver failure: An open randomised controlled trial
Larsen, F. S., Schmidt, L. E., Bernsmeier, C., Rasmussen, A., Isoniemi, H., Patel, V., Triantafyllou, E., Bernal, W., Auzinger, G., Shawcross, D., Eefsen, M., Bjerring, P. N., Clemmesen, J. O., Hockerstedt, K., Frederiksen, H.-J., Hansen, B. A., Antoniades, C. G. & Wendon, J., 1 Jan 2016, In: Journal of Hepatology. 64, 1, p. 69-78Research output: Contribution to journal › Article › peer-review
482 Citations (Scopus) -
Multivariate metabotyping of plasma accurately predicts survival in patients with decompensated cirrhosis.
McPhail, M., Shawcross, D. L., Lewis, M. R., Coltart, I., Want, E. J., Antoniades, C. G., Veselkov, K., Triantafyllou, E., Patel, V. C., Pop, O. T., Gomez-Romero, M., Kyriakides, M., Zia, R., Abeles, R. D., Crossey, M. M. E., Jassem, W., O'Grady, J., Heaton, N., Auzinger, G. & Bernal, W. & 6 others, , May 2016, In: Journal of Hepatology. 64, 5, p. 1058-1067Research output: Contribution to journal › Article › peer-review
Open AccessFile80 Citations (Scopus)362 Downloads (Pure) -
2015
Acute alcoholic hepatitis and cellular Th1 immune responses to alcohol dehydrogenase
Blackmore, L. J., Ryan, J. M., Huang, X., Hussain, M., Triantafyllou, E., Vergis, N., Manakkat Vijay, G., Antoniades, C. G., Thursz, M. R., Jassem, W., Vergani, D., Shawcross, D. L. & Ma, Y., 26 Feb 2015, In: Lancet. 385 , S1, p. S22-S22 1 p., 61.Research output: Contribution to journal › Poster abstract › peer-review
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Patients With Acute-on-Chronic Liver Failure Have Increased Numbers of Regulatory Immune Cells Expressing the Receptor Tyrosine Kinase MERTK
Bernsmeier, C., Pop, O. T., Singanayagam, A., Triantafyllou, E., Patel, V. C., Weston, C. J., Curbishley, S., Sadiq, F., Vergis, N., Khamri, W., Bernal, W., Auzinger, G., Heneghan, M., Ma, Y., Jassem, W., Heaton, N. D., Adams, D. H., Quaglia, A., Thursz, M. R. & Wendon, J. & 1 others, , Mar 2015, In: Gastroenterology. 148, 3, p. 603-615.e14 27 p.Research output: Contribution to journal › Article › peer-review
228 Citations (Scopus) -
PROOF-OF-PRINCIPLE EVALUATION OF IMMUNOMODULATORY DRUGS IN PROMOTING PHAGOCYTOSIS CAPACITY IN PATIENTS WITH LIVER FAILURE.
Bernsmeier, C., Tidswell, R., Ghataore, L., Patel, V. C., Singanayagam, A., Triantafyllou, E., Khamri, W., Heneghan, M., Willars, C., Bernal, W., Auzinger, G., Taylor, D. R., Vincent, R., Ma, Y., Thursz, M. R., Wendon, J. & Antoniades, C., 2015, In: Journal of Hepatology. 62, p. S324 1 p., P1294.Research output: Contribution to journal › Meeting abstract › peer-review
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2014
Could targeting secretory leukocyte protease inhibitor be an effective therapeutic option to prevent infections in acute liver failure?
Possamai, L. A., Khamri, W., Triantafyllou, E., Wendon, J. A., Thursz, M. R. & Antoniades, C. G., 2014, In: Immunotherapy. 6, 6, p. 667-9 3 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Secretory leukocyte protease inhibitor: A pivotal mediator of anti-inflammatory responses in acetaminophen-induced acute liver failure
Antoniades, C. G., Khamri, W., Abeles, R. D., Taams, L. S., Triantafyllou, E., Possamai, L. A., Bernsmeier, C., Mitry, R. R., O'Brien, A., Gilroy, D., Goldin, R., Heneghan, M., Heaton, N., Jassem, W., Bernal, W., Vergani, D., Ma, Y., Quaglia, A., Wendon, J. & Thursz, M., 24 Mar 2014, In: Hepatology. 59, 4, p. 1564-1576 13 p.Research output: Contribution to journal › Article › peer-review
80 Citations (Scopus) -
2013
Increased apoptotic activity is associated with hospital mortality and disruption in lipid homeostasis in acute-on-chronic liver failure.
McPhail, M., Triantafyllou, E., Shawcross, D., Antoniades, C. G., Lewis, M. R., Want, E., Patel, V. C., Pasha, Y., Abeles, D., Bernal, W., Holmes, E., Wendon, J. & Taylor-Robinson, S. D., Oct 2013, In: Hepatology. 58, p. 851A-852A 2 p., 1324.Research output: Contribution to journal › Meeting abstract › peer-review