A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis

Manuel A Rivas, Daniel Graham, Patrick Sulem, Christine Stevens, A Nicole Desch, Philippe Goyette, Daniel Gudbjartsson, Ingileif Jonsdottir, Unnur Thorsteinsdottir, Frauke Degenhardt, Sören Mucha, Mitja I Kurki, Dalin Li, Mauro D'Amato, Vito Annese, Severine Vermeire, Rinse K Weersma, Jonas Halfvarson, Paulina Paavola-Sakki, Maarit LappalainenMonkol Lek, Beryl Cummings, Taru Tukiainen, Talin Haritunians, Leena Halme, Lotta L E Koskinen, Ashwin N Ananthakrishnan, Yang Luo, Graham A Heap, Marijn C Visschedijk, Daniel G MacArthur, Tariq Ahmad, Carl A Anderson, Steven R Brant, Richard H Duerr, Mark S Silverberg, Judy H Cho, Aarno Palotie, Päivi Saavalainen, Kimmo Kontula, Martti Färkkilä, Dermot P B McGovern, Andre Franke, Kari Stefansson, John D Rioux, Ramnik J Xavier, Mark J Daly, C Hawkey, C Mathew, N Prescott, UK IBD Genetics Consortium

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Biochemistry, Genetics and Molecular Biology