Case report: making the CONN-ection: two cases of persistent hypertension and hypokalaemia following renal transplantation

Atul Kumar; Johnathan Hubbard; Mufaddal T Moonim; Simon Steddon; David Goldsmith

doi:10.1007/s11255-011-9924-y

Case report: making the CONN-ection: two cases of persistent hypertension and hypokalaemia following renal transplantation

Atul Kumar^*, Johnathan Hubbard, Mufaddal T Moonim, Simon Steddon, David Goldsmith

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Conn's syndrome following renal transplantation is extremely rare. Here, we present two cases of persistent hypertension and hypokalemia, emerging after kidney transplantation, which proved resistant to medical treatment. In both patients, biochemical investigations elicited massively elevated plasma aldosterone levels and suppressed renin activity. Abdominal MRI demonstrated a 90- and 20-mm right adrenal tumour in cases 1 and 2, respectively. For both patients, curative treatment was achieved via laparoscopic right adrenalectomy.

Original language	English
Pages (from-to)	1577-1580
Number of pages	4
Journal	International Urology and Nephrology
Volume	44
Issue number	5
DOIs	https://doi.org/10.1007/s11255-011-9924-y
Publication status	Published - Oct 2012

Keywords

Primary hyperaldosteronism
Conn's
Tumour
Renal transplant
PRIMARY HYPERALDOSTERONISM
PRIMARY ALDOSTERONISM

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10.1007/s11255-011-9924-y

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title = "Case report: making the CONN-ection: two cases of persistent hypertension and hypokalaemia following renal transplantation",

abstract = "Conn's syndrome following renal transplantation is extremely rare. Here, we present two cases of persistent hypertension and hypokalemia, emerging after kidney transplantation, which proved resistant to medical treatment. In both patients, biochemical investigations elicited massively elevated plasma aldosterone levels and suppressed renin activity. Abdominal MRI demonstrated a 90- and 20-mm right adrenal tumour in cases 1 and 2, respectively. For both patients, curative treatment was achieved via laparoscopic right adrenalectomy.",

keywords = "Primary hyperaldosteronism, Conn's, Tumour, Renal transplant, PRIMARY HYPERALDOSTERONISM, PRIMARY ALDOSTERONISM",

author = "Atul Kumar and Johnathan Hubbard and Moonim, {Mufaddal T} and Simon Steddon and David Goldsmith",

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T2 - two cases of persistent hypertension and hypokalaemia following renal transplantation

AU - Kumar, Atul

AU - Hubbard, Johnathan

AU - Moonim, Mufaddal T

AU - Steddon, Simon

AU - Goldsmith, David

PY - 2012/10

Y1 - 2012/10

N2 - Conn's syndrome following renal transplantation is extremely rare. Here, we present two cases of persistent hypertension and hypokalemia, emerging after kidney transplantation, which proved resistant to medical treatment. In both patients, biochemical investigations elicited massively elevated plasma aldosterone levels and suppressed renin activity. Abdominal MRI demonstrated a 90- and 20-mm right adrenal tumour in cases 1 and 2, respectively. For both patients, curative treatment was achieved via laparoscopic right adrenalectomy.

AB - Conn's syndrome following renal transplantation is extremely rare. Here, we present two cases of persistent hypertension and hypokalemia, emerging after kidney transplantation, which proved resistant to medical treatment. In both patients, biochemical investigations elicited massively elevated plasma aldosterone levels and suppressed renin activity. Abdominal MRI demonstrated a 90- and 20-mm right adrenal tumour in cases 1 and 2, respectively. For both patients, curative treatment was achieved via laparoscopic right adrenalectomy.

KW - Primary hyperaldosteronism

KW - Conn's

KW - Tumour

KW - Renal transplant

KW - PRIMARY HYPERALDOSTERONISM

KW - PRIMARY ALDOSTERONISM

U2 - 10.1007/s11255-011-9924-y

DO - 10.1007/s11255-011-9924-y

M3 - Article

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JO - International Urology and Nephrology

JF - International Urology and Nephrology

IS - 5

ER -

Case report: making the CONN-ection: two cases of persistent hypertension and hypokalaemia following renal transplantation

Abstract

Keywords

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