Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas

Claire Palles, Jean Baptiste Cazier, Kimberley M. Howarth, Enric Domingo, Angela M. Jones, Peter Broderick, Zoe Kemp, Sarah L. Spain, Estrella Guarino Almeida, Israel Salguero, Amy Sherborne, Daniel Chubb, Luis G. Carvajal-Carmona, Yusanne Ma, Kulvinder Kaur, Sara Dobbins, Ella Barclay, Maggie Gorman, Lynn Martin, Michal B. KovacSean Humphray, Anneke Lucassen, Christopher H. Holmes, David Bentley, Peter Donnelly, Jenny Taylor, Christos Petridis, Rebecca Roylance, Elinor Sawyer, David J. Kerr, Susan Clark, Jonathan Grimes, Stephen E. Kearsey, Huw J W Thomas, Gilean McVean, Richard S. Houlston, Ian Tomlinson*, Huw J W Thomas, Eamonn Maher, Gareth Evans, Carole Cummings, Margaret Stevens, Lisa Walker, Dorothy Halliday, Ruth Armstrong, Joan Paterson, Shirley Hodgson, Tessa Homfray, Lucy Side, Louise Izatt, Alan Donaldson, Susan Tomkins, Patrick Morrison, Selina Goodman, Carole Brewer, Alex Henderson, Rosemarie Davidson, Victoria Murday, Jaqueline Cook, Nneva Haites, Timothy Bishop, Eamonn Sheridan, Andrew Green, Christopher Marks, Sue Carpenter, Mary Broughton, Lynn Greenhalge, Mohnish Suri, John Bell, Peter Ratcliffe, Andrew Wilkie, John Broxholme, David Buck, Richard Cornall, Lorna Gregory, Julian Knight, Gerton Lunter, Zoya Kingsbury, Russell Grocock, Edouard Hatton, Christopher C. Holmes, Linda Hughes, Peter Humburg, Alexander Kanapin, Lisa Murray, Andy Rimmer

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

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Biochemistry, Genetics and Molecular Biology