Research output per year
Research output per year
Personal profile
Research interests
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Complex disease genetics and precision medicine
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Big data application and AI in clinical trials and drug discovery
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Development of proteomic-based biomarkers for Neurodegeneration
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Structural variation analysis in genomics
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Medicine, Bachelor of Medicine and Bachelor of Surgery, Cairo University
Neuroscience , Master in Science, Development of proteomic-based biomarkers for Alzheimer disease, Institute of Psychiatry, Psychology and Neuroscience (IoPPN)
Clinical Neuroscience , Doctor of Philosophy, Understanding Disease Trajectory in Amyotrophic Lateral Sclerosis, King's College London
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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C9orf72 Repeat Expansion Discordance in 6 Multigenerational Kindreds
Ryan, M., Doherty, M. A., Al Khleifat, A., Costello, E., Hengeveld, J. C., Heverin, M., Al-Chalabi, A., McLaughlin, R. L. & Hardiman, O., Feb 2024, In: Neurology. Genetics. 10, 1, e200112.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)45 Downloads (Pure) -
Harnessing transcriptomic signals for amyotrophic lateral sclerosis to identify novel drugs and enhance risk prediction
Pain, O., Jones, A., Al Khleifat, A., Agarwal, D., Hramyka, D., Karoui, H., Kubica, J., Llewellyn, D. J., Ranson, J. M., Yao, Z., Iacoangeli, A. & Al-Chalabi, A., 15 Aug 2024, In: Heliyon. 10, 15, e35342.Research output: Contribution to journal › Article › peer-review
Open Access -
Investigating the socioeconomic status impact on amyotrophic lateral sclerosis
Shojaie, A., Al Khleifat, A., Garrahy, S., Habash-Bailey, H., Thomson, R., Martin, S., Javidnia, S., Nigel Leigh, P. & Al-Chalabi, A., 2 Sept 2024, In: Amyotrophic lateral sclerosis & frontotemporal degeneration.Research output: Contribution to journal › Article › peer-review
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Mutations in the tail and rod domains of the neurofilament heavy-chain gene increase the risk of ALS
Project MinE ALS Sequencing Consortium, Jul 2024, In: Annals of Clinical and Translational Neurology. 11, 7, p. 1775-1786 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
predicTTE: An accessible and optimal tool for time-to-event prediction in neurological diseases
Weinreich, M., McDonough, H., Yacovzada, N., Magen, I., Cohen, Y., Harvey, C., Gornall, S., Boddy, S., Alix, J., Mohseni, N., Kurz, J. M., Kenna, K. P., Zhang, S., Iacoangeli, A., Al-Khleifat, A., Snyder, M. P., Hobson, E., Al-Chalabi, A., Hornstein, E. & Elhaik, E. & 3 others, , 23 Jul 2024, (bioRxiv : the preprint server for biology).Research output: Working paper/Preprint › Preprint
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MNDSTaR (MND: MNDSTaR: The King's-LifeArc Solution for Motor Neurone Disease Target Validation
Al Khleifat, A. (Primary Investigator), Al-Chalabi, A. (Co-Investigator), Iacoangeli, A. (Co-Investigator), Mitchell, J. (Co-Investigator) & Smith, B. (Co-Investigator)
1/05/2024 → 30/04/2026
Project: Research
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Validating ALS molecular profiles from the UK biobank as a diagnostic tool
Iacoangeli, A. (Primary Investigator), Al Khleifat, A. (Co-Investigator), Al-Chalabi, A. (Co-Investigator), Breen, G. (Co-Investigator) & Dobson, R. (Co-Investigator)
18/03/2024 → 17/03/2026
Project: Research
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Validating ALS molecular subtypes as biomarkers for patient stratification
Iacoangeli, A. (Primary Investigator), Al Khleifat, A. (Co-Investigator), Al-Chalabi, A. (Co-Investigator) & Breen, G. (Co-Investigator)
1/03/2024 → 31/08/2025
Project: Research
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Validating new promising drug targets in Amyotrophic Lateral Sclerosis
Iacoangeli, A. (Primary Investigator), Al Khleifat, A. (Co-Investigator), Al-Chalabi, A. (Co-Investigator), Mitchell, J. (Co-Investigator), Smith, B. (Co-Investigator) & Sreedharan, J. (Co-Investigator)
1/01/2023 → 1/01/2025
Project: Research
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Toward multiomics-based next-generation diagnostics for precision medicine in ALS and FTD
Al-Chalabi, A. (Primary Investigator) & Al Khleifat, A. (Co-Investigator)
Motor Neurone Disease Association
31/01/2022 → 31/03/2025
Project: Research
Prizes
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ALS Association Milton Safenowitz Research Fellowship
Al Khleifat, A. (Recipient), 31 Jan 2022
Prize: Fellowship awarded competitively
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ENCALS Young Investigator Award
Al Khleifat, A. (Recipient), 3 Jun 2022
Prize: Prize (including medals and awards)
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King's College London Recognition Awards: 2021/2022 Academic Year
Al Khleifat, A. (Recipient), 14 Feb 2022
Prize: Prize (including medals and awards)
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Motor Neurone Disease Association Lady Edith Wolfson Fellowship
Al Khleifat, A. (Recipient), 31 Jan 2022
Prize: Fellowship awarded competitively