Search results

• 2011

  Targeting serpins in high-throughput and structure-based drug design

  Chang, Y.-P., Mahadeva, R., Patschull, A. O. M., Nobeli, I., Ekeowa, U. I., McKay, A. R., Thalassinos, K., Irving, J. A., Haq, I., Nyon, M. P., Christodoulou, J., Ordóñez, A., Miranda, E. & Gooptu, B., 2011, Serpin Structure and Evolution. Whisstock, J. C. & Bird, P. I. (eds.). Academic Press, Vol. 501. p. 139-175 37 p. (Methods in Enzymology; vol. 501).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Serpin 100%
  • Reaction Mechanism 25%
  • Conformational Transition 25%
  • Ligand 25%
  • Conformational Change 20%
  15 Citations (Scopus)

• The serpinopathies: Studying serpin polymerization in vivo

  Irving, J. A., Ekeowa, U. I., Belorgey, D., Haq, I., Gooptu, B., Miranda, E., Pérez, J., Roussel, B. D., Ordóñez, A., Dalton, L. E., Thomas, S. E., Marciniak, S. J., Parfrey, H., Chilvers, E. R., Teckman, J. H., Alam, S., Mahadeva, R., Rashid, S. T., Vallier, L. & Lomas, D. A., 2011, Methods in Enzymology. Whisstock, J. C. & Bird, P. I. (eds.). Academic Press, Vol. 501. p. 421-466 46 p. (Methods in Enzymology; vol. 501).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Polymerization 100%
  • Serpin 100%
  • Protein 50%
  • Animal Models 50%
  • Stem Cell 25%
  31 Citations (Scopus)

• The Structural Biology of α1-antitrypsin and the Serpinopathies

  Gooptu, B. & Lomas, D. A., 2011, Methods in Protein biochemistry. Gottingen: de Gruyter, p. 325-344 20 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter