Research output per year
Research output per year
Personal profile
Research interests
<p>virus-host interactions during HIV-1 infections. Interests include host restriction factors, factors that support HIV-1 replication and the metabolic demand exerted by HIV infections.</p>
Research interests (short)
Human immunodeficiency virus; restriction factors; virus-host interactions; protein structure; homology modelling;
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Hendrik Huthoff is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
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Upregulation of Glucose Uptake and Hexokinase Activity of Primary Human CD4+ T Cells in Response to Infection with HIV-1
Kavanagh Williamson, M., Coombes, N., Juszczak, F., Athanasopoulos, M., Khan, M., Eykyn, T., Srenathan, U., Taams, L., Dias Zeidler, J., Da Poian, A. & Huthoff, H., 7 Mar 2018, (E-pub ahead of print) In: Viruses-Basel. 10, 3, p. 114Research output: Contribution to journal › Article › peer-review
Open AccessFile65 Citations (Scopus)224 Downloads (Pure) -
Evidence for altered glutamine metabolism in HIV-1 infected primary human CD4+ T cells
Hegedus, A., Kavanagh Williamson, M., Khan, M. B., Dias Zeidler, J., Da Poian, A., El Bacha, T., Struys, E. & Huthoff, H., 1 Dec 2017, In: Aids Research and Human Retroviruses.Research output: Contribution to journal › Article › peer-review
Open AccessFile39 Citations (Scopus)126 Downloads (Pure) -
HIV-1 pathogenicity and virion production are dependent on the metabolic phenotype of activated CD4+ T cells
Hegedus, A., Kavanagh Williamson, M. & Huthoff, H., 25 Nov 2014, In: Retrovirology. 11, 98Research output: Contribution to journal › Article › peer-review
Open Access82 Citations (Scopus) -
Rationalisation of the Differences between APOBEC3G Structures from Crystallography and NMR Studies by Molecular Dynamics Simulations
Autore, F., Bergeron, J. R. C., Malim, M. H., Fraternali, F. & Huthoff, H., 2010, In: PL o S One . 5, 7, e11515.Research output: Contribution to journal › Article › peer-review
17 Citations (Scopus) -
The SOCS-box of HIV-1 Vif interacts with ElonginBC by induced-folding to recruit its Cul5-containing ubiquitin ligase complex
Bergeron, J. R. C., Huthoff, H., Veselkov, D. A., Beavil, R. L., Simpson, P. J., Matthews, S. J., Malim, M. H. & Sanderson, M. R., Jun 2010, In: PL o S Pathogens. 6, 6, e1000925.Research output: Contribution to journal › Article › peer-review
72 Citations (Scopus)
Projects
- 11 Finished
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MULTIOMICA - Methodologies for the integrative analysis of Multiomics data
Gomez Cabrero Lopez, D. (Primary Investigator) & Huthoff, H. (Co-Investigator)
1/10/2017 → 30/09/2021
Project: Research
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Development of molecular tools to investigate Zika virus tropism and pathogenicity.
Catanese, M. T. (Primary Investigator), Campbell, A. (Co-Investigator), Fleck, R. (Co-Investigator), Huthoff, H. (Co-Investigator), Malim, M. (Co-Investigator) & Neil, S. (Co-Investigator)
1/04/2016 → 1/10/2017
Project: Research
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Dengue virus-mediated manipulation of cellular metabolism as a marker for disease severity and progression
Huthoff, H. (Primary Investigator)
15/01/2016 → 14/01/2018
Project: Research
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Exploring the metabolic dependency of HIV-1 replication
Huthoff, H. (Primary Investigator) & Hegedus, A. (Co-Investigator)
9/07/2015 → 8/07/2018
Project: Research
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Newton001: The dependency of HIV-1 and dengue virus infections on host metabolism as novel targets for antiviral therapy
Huthoff, H. (Primary Investigator) & Hegedus, A. (Co-Investigator)
1/01/2015 → 30/01/2016
Project: Research
Activities
- 1 Publication peer-review
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Nucleic Acids research and the Journal of Biological Chemistry (Journal)
Huthoff, H. (Editor)
2001 → …Activity: Publication peer-review and editorial work › Publication peer-review
Prizes
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year fellowship from the American Foundation for Aids Research (AmfAR)
Huthoff, H. (Recipient), 2001
Prize: Fellowship awarded competitively