Research output per year
Research output per year
Personal profile
Research interests
Work carried out in my laboratory first demonstrated an involvement of EphB receptor tyrosine kinases and their ephrinB ligands in the onset of inflammatory pain. My main interests are in exploring further the involvement of this signalling system in the onset and maintenance of different types of chronic pain (inflammatory and neuropatjic), acting both at central and peripheral level, and mediating communication between glial and neuronal cells, as well as between neurons.
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Research interests (short)
Involvement of EphB receptors and ephrinB ligands in chronic pain.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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- 1 Similar Profiles
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Ephb receptors and persistent pain
Gavazzi, I., 5 Mar 2016, An Introduction to Pain and Nervous System Disorders. WILEY-BLACKWELL, p. 201-224 24 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
2 Citations (Scopus) -
Involvement of EphB1 Receptors Signalling in Models of Inflammatory and Neuropathic Pain
Cibert-Goton, V., Yuan, G., Battaglia, A., Fredriksson, S., Henkemeyer, M., Sears, T. & Gavazzi, I., 16 Jan 2013, In: PLoS ONE. 8, 1, e53673.Research output: Contribution to journal › Article › peer-review
31 Citations (Scopus) -
Nociceptor-expressed ephrin-B2 regulates inflammatory and neuropathic pain
Zhao, J., Yuan, G., Cendan, C. M., Nassar, M. A., Lagerstrom, M. C., Kullander, K., Gavazzi, I. & Wood, J. N., 8 Nov 2010, In: Molecular Pain. 6, 77.Research output: Contribution to journal › Article › peer-review
48 Citations (Scopus) -
EphrinB2 induces tyrosine phosphorylation of NR2B via Src-family kinases during inflammatory hyperalgesia
Slack, S., Battaglia, A., Cibert-Goton, V. & Gavazzi, I., 22 Sept 2008, In: Neuroscience. 156, 1, p. 175-183 9 p.Research output: Contribution to journal › Article › peer-review
67 Citations (Scopus) -
Tamoxifen-inducible Na(v)1.8-CreERT2 recombinase activity in nociceptive neurons of dorsal root ganglia
Zhao, J., Nassarl, M. A., Gavazzi, I. & Wood, J. N., Aug 2006, In: GENESIS. 44, 8, p. 364 - 371 8 p.Research output: Contribution to journal › Article › peer-review
23 Citations (Scopus)
Projects
- 5 Finished
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Regulation of synaptic efficacy and behaviour by eprhin-B2
Gavazzi, I. (Primary Investigator)
BBSRC Biotechnology and Biological Sciences Research Council
28/02/2005 → 27/06/2008
Project: Research
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Targeting Eph/Ephrin mediated inhibition at the damaged dorsal root entry zone (DREZ)
Gavazzi, I. (Primary Investigator)
International Spinal Research Trust
1/05/2004 → 30/04/2008
Project: Research
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EphB receptors and spinal processing of pain
Gavazzi, I. (Primary Investigator)
1/11/2003 → 31/10/2007
Project: Research
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Eph receptors and ephrins: expression patterns and function in adult sensory systems
Gavazzi, I. (Primary Investigator) & McMahon, S. (Primary Investigator)
1/05/2000 → 30/04/2002
Project: Research
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Specificity of regenerating sensory axons: studies in an in vivo model system.
Gavazzi, I. (Primary Investigator)
30/04/1997 → 28/04/2000
Project: Research
Activities
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BBSRC
Gavazzi, I. (Member)
2001 → …Activity: Other › Types of External academic engagement - Membership of external research organisation
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Wellcome Trust
Gavazzi, I. (Member)
2001 → …Activity: Other › Types of External academic engagement - Membership of external research organisation
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Journal of Neuroscience (Journal)
Gavazzi, I. (Editor)
2001 → …Activity: Publication peer-review and editorial work › Publication peer-review
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Journal of Neurochemistry (Journal)
Gavazzi, I. (Editor)
2001 → …Activity: Publication peer-review and editorial work › Publication peer-review
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Brain (Journal)
Gavazzi, I. (Editor)
2001 → …Activity: Publication peer-review and editorial work › Publication peer-review