Research output per year
Research output per year
Personal profile
Research interests
The lab is interested in understanding how neural circuits are formed, in particular how signaling events that regulate the cytoskeleton lead to morphogenesis. Much of our work emphasises on genetics, cell and developmental biology, using neurons in the Drosophila brain as a model. Our work showed that Rho GTPases are critical mediators, and that they act through multiple pathways to regulate distinct aspects of axonal morphogenesis (Neuron 2004, 44, 779-793; Nature 2002, 416, 442-447). Our current work is focused on further understanding how different axon guidance signals contribute to this process during brain development.
Research interests (short)
Axon guidance in the Drosophila brain: Rho GTPases and cytoskeletal regulatory pathways.
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Research output
- 6 Article
-
Wnt/PCP proteins regulate stereotyped axon branch extension in Drosophila
Ng, J., 1 Jan 2012, In: Development (Cambridge): for advances in developmental biology and stem cells. 139, 1, p. 165 - 177 13 p.Research output: Contribution to journal › Article › peer-review
39 Citations (Scopus) -
Signal strength and signal duration define two distinct aspects of JNK-regulated axon stability
Rallis, A., Moore, C. & Ng, J., Mar 2010, In: Developmental Biology. 339, 1, p. 65 - 77 13 p.Research output: Contribution to journal › Article › peer-review
25 Citations (Scopus) -
Rho GTPases regulate axon growth through convergent and divergent signaling pathways
Ng, J. & Luo, L., 2 Dec 2004, In: Neuron. 44, 5, p. 779 - 793 15 p.Research output: Contribution to journal › Article › peer-review
163 Citations (Scopus) -
Rac promotes epithelial cell rearrangement during tracheal tubulogenesis in Drosophila
Chihara, T., Kato, K., Taniguchi, M., Ng, J. & Hayashi, S., Apr 2003, In: Development (Cambridge): for advances in developmental biology and stem cells. 130, 7, p. 1419 - 1428 10 p.Research output: Contribution to journal › Article › peer-review
88 Citations (Scopus) -
Rac function and regulation during Drosophila development
Hakeda-Suzuki, S., Ng, J., Tzu, J., Dietzl, G., Sun, Y., Harms, M., Nardine, T., Luo, L. & Dickson, B. J., 28 Mar 2002, In: NATURE. 416, 6879, p. 438 - 442 5 p.Research output: Contribution to journal › Article › peer-review
305 Citations (Scopus)
Projects
- 10 Finished
-
Role of JNK signalling in axon degeneration
Ng, J. (Primary Investigator)
1/03/2012 → 28/02/2015
Project: Research
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Modelling the role of JNK signalling in human neurodegeneration
Ng, J. (Primary Investigator)
1/10/2011 → 30/09/2016
Project: Research
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Role of TGFbeta signalling in neural connectivity
Ng, J. (Primary Investigator)
1/12/2010 → 30/11/2013
Project: Research
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Role of transforming growth factor beta signals in axonal morphogenesis
Ng, J. (Primary Investigator)
1/06/2010 → 31/05/2015
Project: Research
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Role of transforming growth factor-beta signals in axonal morphogenesis
Ng, J. (Primary Investigator)
1/06/2010 → 31/05/2015
Project: Research