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Julian Ng

Dr

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Research interests

The lab is interested in understanding how neural circuits are formed, in particular how signaling events that regulate the cytoskeleton lead to morphogenesis. Much of our work emphasises on genetics, cell and developmental biology, using neurons in the Drosophila brain as a model. Our work showed that Rho GTPases are critical mediators, and that they act through multiple pathways to regulate distinct aspects of axonal morphogenesis (Neuron 2004, 44, 779-793; Nature 2002, 416, 442-447). Our current work is focused on further understanding how different axon guidance signals contribute to this process during brain development.

Research interests (short)

Axon guidance in the Drosophila brain: Rho GTPases and cytoskeletal regulatory pathways.

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