Search results

• 2022

  OCT2013, AN ISCHAEMIA-ACTIVATED ANTIARRHYTHMIC PRODRUG, DEVOID OF THE SYSTEMIC SIDE EFFECTS OF LIDOCAINE

  Hesketh, L. M., Sikkel, M. B., Mahoney-Sanchez, L., Mazzacuva, F., Chowdhury, R. A., Tzortzis, K. N., Firth, J., Winter, J., MacLeod, K. T., Ogrodzinski, S., Wilder, C. D. E., Patterson, L. H., Peters, N. S. & Curtis, M., May 2022, In: British Journal of Pharmacology. 179, 9, p. 2037-2053 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  • Side Effect 100%
  • Ischemia 100%
  • Lidocaine 100%
  • Antiarrhythmic Agent 100%
  • Ventricular Fibrillation 28%
  4 Citations (Scopus)

  54 Downloads (Pure)
• 2020

  Characterisation of mexiletine’s translational therapeutic index for suppression of ischaemia-induced ventricular fibrillation in the rat isolated heart

  Hesketh, L. M., Wilder, C. D. E., Ranadive, N. N., Lytra, G., Qazimi, P., Munro, J. S., Ahdi, N. & Curtis, M. J., 1 Dec 2020, In: Scientific Reports. 10, 1, 8397 .

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  • Mexiletine 100%
  1 Citation (Scopus)

  123 Downloads (Pure)