Research output per year
Research output per year
Personal profile
Research interests
The laboratory studies cells that mediate asthma, we are interested in how gene expression is both upregulated and repressed and the molecular basis of glucocorticoid resistance in asthmatic patients.
Research interests (short)
Transcription, chromatin, asthma.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Defective STAT5 Activation and Aberrant Expression of BCL6 in Naive CD4 T Cells Enhances Follicular Th Cell-like Differentiation in Patients with Granulomatosis with Polyangiitis
Kim, S., Boehme, L., Nel, L., Casian, A., Sangle, S., Nova-Lamperti, E., Seitan, V., Spencer, J., Lavender, P., D'Cruz, D. P. & John, S., 15 Feb 2022, In: Journal of immunology (Baltimore, Md. : 1950). 208, 4, p. 807-818 12 p.Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus) -
Exosome-mediated RNAi of PAK4 prolongs survival of pancreatic cancer mouse model after loco-regional treatment
Xu, L., Faruqu, F. N., Lim, Y. M., Lim, K. Y., Liam-Or, R., Walters, A. A., Lavender, P., Fear, D., Wells, C. M., Tzu-Wen Wang, J. & Al-Jamal, K. T., Jan 2021, In: Biomaterials. 264, 120369.Research output: Contribution to journal › Article › peer-review
51 Citations (Scopus) -
Interleukin-22 orchestrates a pathological endoplasmic reticulum stress response transcriptional programme in colonic epithelial cells
Powell, N., Pantazi, E., Pavlidis, P., Tsakmaki, A., Li, K., Yang, F., Parker, A., Pin, C., Cozzetto, D., Minns, D., Stolarczyk, E., Saveljeva, S., Mohamed, R., Lavender, P., Afzali, B., Digby-Bell, J., Tjir-Li, T., Kaser, A., Friedman, J. & MacDonald, T. T. & 2 others, , 7 Feb 2020, In: Gut. 69, 3, p. 578-590 13 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile81 Citations (Scopus)136 Downloads (Pure) -
The cholesterol biosynthesis pathway regulates IL-10 expression in human Th1 cells
Perucha, E., Melchiotti, R., Bibby, J., Wu, W., Stensgaard Frederiksen, K., Roberts, C., Hall, Z., LeFriec, G., Robertson, K., Lavender, P., Gammeltoft Gerwien, J., Taams, L., Griffin, J., de Rinaldis, E., van Baarsen, L., Kemper, C., Ghazal, P. & Cope, A., 30 Jan 2019, In: Nature Communications. 10, 1, 13 p., 498.Research output: Contribution to journal › Article › peer-review
Open AccessFile95 Citations (Scopus)145 Downloads (Pure) -
Activation-Associated Accelerated Apoptosis of Memory B Cells in Critically Ill Patients With Sepsis
Shankar-Hari, M., Fear, D., Lavender, P., Mare, T., Beale, R., Swanson, C., Singer, M. & Spencer, J., May 2017, In: Critical Care Medicine. 45, 5, p. 875-882 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile77 Citations (Scopus)447 Downloads (Pure)