Research output per year
Research output per year
Personal profile
Research interests
Molecular genetics and genotype/phenotype correlation in inherited red blood cell disorders, thalassaemia and other haemoglobinopathies.<br />
Research interests (short)
Molecular genetics and genotype/phenotype correlation in inherited red blood cell disorders, thalassaemia and other haemoglobinopathies.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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- 1 Similar Profiles
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Mixed T-Cell Chimerism after Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia Using an Alemtuzumab-Containing Regimen is Shaped by Persistence of Recipient CD8 T Cells
Grimaldi, F., Potter, V., Perez-Abellan, P., Veluchamy, J. P., Atif, M., Grain, R., Sen, M., Best, S., Lea, N., Rice, C., Pagliuca, A., Mufti, G. J., Marsh, J. C. W. & Barber, L. D., 1 Feb 2017, In: BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. 23, 2, p. 293-299Research output: Contribution to journal › Article › peer-review
Open AccessFile29 Citations (Scopus)521 Downloads (Pure) -
Preclinical modeling of myelodysplastic syndromes
Rouault-Pierre, K., Mian, S. A., Goulard, M., Abarrategi, A., Di Tulio, A., Smith, A. E., Mohamedali, A., Best, S., Nloga, A. M., Kulasekararaj, A. G., Ades, L., Chomienne, C., Fenaux, P., Dosquet, C., Mufti, G. J. & Bonnet, D., 1 Dec 2017, In: Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. 31, 12, p. 2702-2708 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile32 Citations (Scopus)185 Downloads (Pure) -
High concordance of genomic and cytogenetic aberrations between peripheral blood and bone marrow in myelodysplastic syndrome (MDS)
Mohamedali, A. M., Gäken, J., Ahmed, M., Malik, F., Smith, A. E., Best, S., Mian, S., Gaymes, T., Ireland, R., Kulasekararaj, A. G. & Mufti, G. J., 4 Sept 2015, In: Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. 29, 9, p. 1928-1938 11 p.Research output: Contribution to journal › Article › peer-review
40 Citations (Scopus) -
A Twins Heritability Study on Alpha Hemoglobin Stabilizing Protein (AHSP) Expression Variability
Lai, M. I., Garner, C., Jiang, J., Silver, N., Best, S., Menzel, S. & Thein, S. L., Dec 2010, In: TWIN RESEARCH AND HUMAN GENETICS. 13, 6, p. 567 - 572 6 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Binding patterns of BCL11A in the globin and GATA1 loci and characterization of the BCL11A fetal hemoglobin locus
Jawaid, K., Wahlberg, K., Thein, S. L. & Best, S., Aug 2010, In: Blood Cells Molecules and Diseases. 45, 2, p. 140 - 146 7 p.Research output: Contribution to journal › Article › peer-review
54 Citations (Scopus)
Projects
- 6 Finished
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Regulation of MYB, a key gene affecting the severity of sickle cell disease
Best, S. (Primary Investigator) & Thein, S. L. (Co-Investigator)
1/09/2011 → 31/08/2014
Project: Research
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Investigating transcription factor binding at the -158 Xmnl promoter polymorphism of the foetal haemoglobin gene and its role in the haemoglobinopathies.
Best, S. (Primary Investigator)
29/06/2010 → 28/08/2010
Project: Research
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Investigating transcription factor binding at the -158 Xmnl promoter polymorphism of the foetal haemoglobin gene and its role in the haemoglobinopathies
Best, S. (Primary Investigator)
29/06/2009 → 31/08/2009
Project: Research
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Investigating transcription factor binding at the -158 xmnl promoter polymorphism of the foetal haemoglobin gene and its role in haemoglobinopathies
Best, S. (Primary Investigator)
29/06/2009 → 28/08/2009
Project: Research
-
Start Up Grant
Best, S. (Primary Investigator) & Thein, S. L. (Co-Investigator)
British Society for Haematology
1/09/2008 → 31/08/2009
Project: Research