Abstract
We report on the synthesis of [2]rotaxanes driven by stabilization of the axle-forming transition state. A bifunctional macrocycle, with hydrogen bond donors at one end and acceptors at the other, is used to stabilize the charges that develop during the addition of a primary amine to a cyclic sulfate.
Original language | English |
---|---|
Pages (from-to) | 8455-8457 |
Number of pages | 3 |
Journal | Journal of the American Chemical Society |
Volume | 139 |
Issue number | 25 |
DOIs | |
Publication status | Published - 28 Jun 2017 |