[2]Rotaxane Formation by Transition State Stabilization

Guillaume De Bo, Guillaume Dolphijn, Charlie T. McTernan, David A. Leigh*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

49 Citations (Scopus)

Abstract

We report on the synthesis of [2]rotaxanes driven by stabilization of the axle-forming transition state. A bifunctional macrocycle, with hydrogen bond donors at one end and acceptors at the other, is used to stabilize the charges that develop during the addition of a primary amine to a cyclic sulfate.

Original languageEnglish
Pages (from-to)8455-8457
Number of pages3
JournalJournal of the American Chemical Society
Volume139
Issue number25
DOIs
Publication statusPublished - 28 Jun 2017

Fingerprint

Dive into the research topics of '[2]Rotaxane Formation by Transition State Stabilization'. Together they form a unique fingerprint.

Cite this