TY - JOUR
T1 - 3D printing in Ophthalmology
T2 - From medical implants to personalised medicine
AU - Tan, Greymi
AU - Ioannou, Nicole
AU - Mathew, Essyrose
AU - Tagalakis, Aristides D.
AU - Lamprou, Dimitrios A.
AU - Yu-Wai-Man, Cynthia
N1 - Funding Information:
This work is supported by the Medical Research Council (MRC, UK, grant number MR/T027932/1 ).
Publisher Copyright:
© 2022 The Author(s)
PY - 2022/9/25
Y1 - 2022/9/25
N2 - 3D printing was invented thirty years ago. However, its application in healthcare became prominent only in recent years to provide solutions for drug delivery and clinical challenges, and is constantly evolving. This cost-efficient technique utilises biocompatible materials and is used to develop model implants to provide a greater understanding of human anatomy and diseases, and can be used for organ transplants, surgical planning and for the manufacturing of advanced drug delivery systems. In addition, 3D printed medical devices and implants can be customised for each patient to provide a more tailored treatment approach. The advantages and applications of 3D printing can be used to treat patients with different eye conditions, with advances in 3D bioprinting offering novel therapy applications in ophthalmology. The purpose of this review paper is to provide an in-depth understanding of the applications and advantages of 3D printing in treating different ocular conditions in the cornea, glaucoma, retina, lids and orbits.
AB - 3D printing was invented thirty years ago. However, its application in healthcare became prominent only in recent years to provide solutions for drug delivery and clinical challenges, and is constantly evolving. This cost-efficient technique utilises biocompatible materials and is used to develop model implants to provide a greater understanding of human anatomy and diseases, and can be used for organ transplants, surgical planning and for the manufacturing of advanced drug delivery systems. In addition, 3D printed medical devices and implants can be customised for each patient to provide a more tailored treatment approach. The advantages and applications of 3D printing can be used to treat patients with different eye conditions, with advances in 3D bioprinting offering novel therapy applications in ophthalmology. The purpose of this review paper is to provide an in-depth understanding of the applications and advantages of 3D printing in treating different ocular conditions in the cornea, glaucoma, retina, lids and orbits.
KW - 3D printing
KW - Drug delivery
KW - Implants
KW - Ophthalmology
KW - Personalised medicine
UR - http://www.scopus.com/inward/record.url?scp=85135939697&partnerID=8YFLogxK
U2 - 10.1016/j.ijpharm.2022.122094
DO - 10.1016/j.ijpharm.2022.122094
M3 - Review article
C2 - 35952803
AN - SCOPUS:85135939697
SN - 0378-5173
VL - 625
JO - INTERNATIONAL JOURNAL OF PHARMACEUTICS
JF - INTERNATIONAL JOURNAL OF PHARMACEUTICS
M1 - 122094
ER -