A high-fat diet impairs cardiac high-energy phosphate metabolism and cognitive function in healthy human subjects

Cameron J Holloway; Lowri E Cochlin; Yaso Emmanuel; Andrew Murray; Ion Codreanu; Lindsay M Edwards; Cezary Szmigielski; Damian J Tyler; Nicholas S Knight; Brian K Saxby; Bridget Lambert; Campbell Thompson; Stefan Neubauer; Kieran Clarke

doi:10.3945/ajcn.110.002758

A high-fat diet impairs cardiac high-energy phosphate metabolism and cognitive function in healthy human subjects

Cameron J Holloway, Lowri E Cochlin, Yaso Emmanuel, Andrew Murray, Ion Codreanu, Lindsay M Edwards, Cezary Szmigielski, Damian J Tyler, Nicholas S Knight, Brian K Saxby, Bridget Lambert, Campbell Thompson, Stefan Neubauer, Kieran Clarke

Centre for Human & Applied Physiological Sciences

Research output: Contribution to journal › Article › peer-review

136 Citations (Scopus)

Abstract

High-fat, low-carbohydrate diets are widely used for weight reduction, but they may also have detrimental effects via increased circulating free fatty acid concentrations.

Original language	English
Pages (from-to)	748-55
Number of pages	8
Journal	The American journal of clinical nutrition
Volume	93
Issue number	4
DOIs	https://doi.org/10.3945/ajcn.110.002758
Publication status	Published - 2011

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Holloway, C. J., Cochlin, L. E., Emmanuel, Y., Murray, A., Codreanu, I., Edwards, L. M., Szmigielski, C., Tyler, D. J., Knight, N. S., Saxby, B. K., Lambert, B., Thompson, C., Neubauer, S., & Clarke, K. (2011). A high-fat diet impairs cardiac high-energy phosphate metabolism and cognitive function in healthy human subjects. The American journal of clinical nutrition, 93(4), 748-55. https://doi.org/10.3945/ajcn.110.002758

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title = "A high-fat diet impairs cardiac high-energy phosphate metabolism and cognitive function in healthy human subjects",

abstract = "High-fat, low-carbohydrate diets are widely used for weight reduction, but they may also have detrimental effects via increased circulating free fatty acid concentrations.",

author = "Holloway, {Cameron J} and Cochlin, {Lowri E} and Yaso Emmanuel and Andrew Murray and Ion Codreanu and Edwards, {Lindsay M} and Cezary Szmigielski and Tyler, {Damian J} and Knight, {Nicholas S} and Saxby, {Brian K} and Bridget Lambert and Campbell Thompson and Stefan Neubauer and Kieran Clarke",

year = "2011",

doi = "10.3945/ajcn.110.002758",

language = "English",

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journal = "The American journal of clinical nutrition",

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Holloway, CJ, Cochlin, LE, Emmanuel, Y, Murray, A, Codreanu, I, Edwards, LM, Szmigielski, C, Tyler, DJ, Knight, NS, Saxby, BK, Lambert, B, Thompson, C, Neubauer, S & Clarke, K 2011, 'A high-fat diet impairs cardiac high-energy phosphate metabolism and cognitive function in healthy human subjects', The American journal of clinical nutrition, vol. 93, no. 4, pp. 748-55. https://doi.org/10.3945/ajcn.110.002758

TY - JOUR

T1 - A high-fat diet impairs cardiac high-energy phosphate metabolism and cognitive function in healthy human subjects

AU - Holloway, Cameron J

AU - Cochlin, Lowri E

AU - Emmanuel, Yaso

AU - Murray, Andrew

AU - Codreanu, Ion

AU - Edwards, Lindsay M

AU - Szmigielski, Cezary

AU - Tyler, Damian J

AU - Knight, Nicholas S

AU - Saxby, Brian K

AU - Lambert, Bridget

AU - Thompson, Campbell

AU - Neubauer, Stefan

AU - Clarke, Kieran

PY - 2011

Y1 - 2011

N2 - High-fat, low-carbohydrate diets are widely used for weight reduction, but they may also have detrimental effects via increased circulating free fatty acid concentrations.

AB - High-fat, low-carbohydrate diets are widely used for weight reduction, but they may also have detrimental effects via increased circulating free fatty acid concentrations.

U2 - 10.3945/ajcn.110.002758

DO - 10.3945/ajcn.110.002758

M3 - Article

C2 - 21270386

SN - 1938-3207

VL - 93

SP - 748

EP - 755

JO - The American journal of clinical nutrition

JF - The American journal of clinical nutrition

IS - 4

ER -

A high-fat diet impairs cardiac high-energy phosphate metabolism and cognitive function in healthy human subjects

Abstract

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