Alternatives to Traditional Per-Oral Endoscopy for Screening

Judith Offman; Rebecca C Fitzgerald

doi:10.1016/j.giec.2017.02.002

Alternatives to Traditional Per-Oral Endoscopy for Screening

Judith Offman, Rebecca C Fitzgerald

MRC Cancer Unit, Hutchinson/MRC Research Centre, University of Cambridge, Box 197, Cambridge Biomedical Campus, Cambridge CB2 0XZ, UK.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

11 Citations (Scopus)

Abstract

Barrett's esophagus (BE) predisposes patients to esophageal adenocarcinoma. 3 to 6% of individuals with gastro-esophageal reflux disease are estimated to have BE but only 20 to 25% of BE patients are currently diagnosed. The current gold standard for diagnosis of BE is per-oral upper GI endoscopy. As this is not suitable for large-scale screening, a number of alternative methods are currently being investigated: transnasal and video capsule endoscopy, endomicroscopy, cell collection devices like the cytosponge and biomarkers. Some of these are promising, however, well powered studies carried out in relevant screening populations are needed.

Original language	English
Title of host publication	Clinical Review Articles
Pages	379-396
Number of pages	18
Volume	27
Edition	3
DOIs	https://doi.org/10.1016/j.giec.2017.02.002
Publication status	Published - Jul 2017

Publication series

Name	Gastrointestinal Endoscopy Clinics of North America
Publisher	W.B. Saunders Ltd
ISSN (Print)	1052-5157

Keywords

Adenocarcinoma/diagnosis
Barrett Esophagus/complications
Capsule Endoscopy
Endoscopy, Digestive System
Esophageal Neoplasms/diagnosis
Esophagoscopy
Gastroesophageal Reflux/complications
Humans

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title = "Alternatives to Traditional Per-Oral Endoscopy for Screening",

abstract = "Barrett's esophagus (BE) predisposes patients to esophageal adenocarcinoma. 3 to 6% of individuals with gastro-esophageal reflux disease are estimated to have BE but only 20 to 25% of BE patients are currently diagnosed. The current gold standard for diagnosis of BE is per-oral upper GI endoscopy. As this is not suitable for large-scale screening, a number of alternative methods are currently being investigated: transnasal and video capsule endoscopy, endomicroscopy, cell collection devices like the cytosponge and biomarkers. Some of these are promising, however, well powered studies carried out in relevant screening populations are needed.",

keywords = "Adenocarcinoma/diagnosis, Barrett Esophagus/complications, Capsule Endoscopy, Endoscopy, Digestive System, Esophageal Neoplasms/diagnosis, Esophagoscopy, Gastroesophageal Reflux/complications, Humans",

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AB - Barrett's esophagus (BE) predisposes patients to esophageal adenocarcinoma. 3 to 6% of individuals with gastro-esophageal reflux disease are estimated to have BE but only 20 to 25% of BE patients are currently diagnosed. The current gold standard for diagnosis of BE is per-oral upper GI endoscopy. As this is not suitable for large-scale screening, a number of alternative methods are currently being investigated: transnasal and video capsule endoscopy, endomicroscopy, cell collection devices like the cytosponge and biomarkers. Some of these are promising, however, well powered studies carried out in relevant screening populations are needed.

KW - Adenocarcinoma/diagnosis

KW - Barrett Esophagus/complications

KW - Capsule Endoscopy

KW - Endoscopy, Digestive System

KW - Esophageal Neoplasms/diagnosis

KW - Esophagoscopy

KW - Gastroesophageal Reflux/complications

KW - Humans

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DO - 10.1016/j.giec.2017.02.002

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T3 - Gastrointestinal Endoscopy Clinics of North America

SP - 379

EP - 396

BT - Clinical Review Articles

ER -

Alternatives to Traditional Per-Oral Endoscopy for Screening

Abstract

Publication series

Keywords

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