Anti-16-kilodalton mycobacterial protein immunoglobulin m levels in healthy but purified protein derivative-reactive children decrease after chemnoprophylaxis

G Sireci, F Dieli, D Di Liberto, S Buccheri, M P La Manna, F Scarpa, P Macaluso, A Romano, L Titone, P Carlo, M Singh, J Ivanyi, A Salerno

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9 Citations (Scopus)

Abstract

Serum responses against Mycobacterium tuberculosis HSP16 were determined for children with tuberculosis (TB) and for healthy purified protein derivative (PPD)-positive and PPD-negative children. Immunoglobulin G (IgG) and IgM responses were higher for TB patients than for other groups. After chemotherapy, IgM and IgG responses decreased for TB patients and PPD-positive subjects. Monitoring of anti-M. tuberculosis HSP16 responses could assist in the management of pediatric TB
Original languageEnglish
Pages (from-to)1231 - 1234
Number of pages4
JournalCLINICAL AND VACCINE IMMUNOLOGY
Volume14
Issue number9
DOIs
Publication statusPublished - Sept 2007

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