Are there genetic influences on addiction: evidence from family, adoption and twin studies

Arpana Agrawal, Michael T Lynskey

Research output: Contribution to journalArticlepeer-review

319 Citations (Scopus)

Abstract

In this exciting era of gene discovery, we review evidence from family, adoption and twin studies that examine the genetic basis for addiction. With a focus on the classical twin design that utilizes data on monozygotic and dizygotic twins, we discuss support in favor of heritable influences on alcohol, nicotine, cannabis and other illicit drug dependence.
Original languageEnglish
Pages (from-to)1069-81
Number of pages13
JournalAddiction
Volume103
Issue number7
DOIs
Publication statusPublished - Jul 2008

Keywords

  • Behavior, Addictive
  • Evidence-Based Medicine
  • Humans
  • Diseases in Twins
  • Adoption
  • Twins, Dizygotic
  • Age Distribution
  • Twins, Monozygotic
  • Risk Factors
  • Substance-Related Disorders
  • Family
  • Genetic Predisposition to Disease
  • Sex Distribution
  • Female
  • Male
  • Social Environment

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