TY - JOUR
T1 - BEN/DM-GRASP/SC1 expression during mouse facial development: differential expression and regulation in molars and incisors
AU - Fraboulet, S
AU - Kavvadia, K
AU - Pourquie, O
AU - Sharpe, P T
AU - Mitsiadis, T A
PY - 2003/6
Y1 - 2003/6
N2 - The cell adhesion molecule BEN/DM-GRASP/SC1 is expressed in a variety of tissues during embryogenesis. Here, we studied the expression pattern of BEN/DM-GRASP/SC1 in different organs involved in facial mouse development, especially in the developing teeth. BEN/DM-GRASP/SC1 was expressed in nose, whisker, gland, and tongue epithelia, as well as in myogenic mesenchyme. In molars, BEN/DM-GRASP/SC1 was firstly expressed in the condensed mesenchyme and thereafter expression was confined to mesenchymal cells of the dental follicle. In contrast, in incisors, transient BEN/DM-GRASP/SC1 expression was restricted to epithelium. In tissue recombination experiments, BEN/DM-GRASP/SC1 expression in mesenchyme was activated by molar, but not incisor epithelium. (C) 2003 Elsevier Science B.V. All rights reserved.
AB - The cell adhesion molecule BEN/DM-GRASP/SC1 is expressed in a variety of tissues during embryogenesis. Here, we studied the expression pattern of BEN/DM-GRASP/SC1 in different organs involved in facial mouse development, especially in the developing teeth. BEN/DM-GRASP/SC1 was expressed in nose, whisker, gland, and tongue epithelia, as well as in myogenic mesenchyme. In molars, BEN/DM-GRASP/SC1 was firstly expressed in the condensed mesenchyme and thereafter expression was confined to mesenchymal cells of the dental follicle. In contrast, in incisors, transient BEN/DM-GRASP/SC1 expression was restricted to epithelium. In tissue recombination experiments, BEN/DM-GRASP/SC1 expression in mesenchyme was activated by molar, but not incisor epithelium. (C) 2003 Elsevier Science B.V. All rights reserved.
UR - http://www.scopus.com/inward/record.url?scp=0037942824&partnerID=8YFLogxK
U2 - 10.1016/S1567-133X(03)00049-8
DO - 10.1016/S1567-133X(03)00049-8
M3 - Article
VL - 3
SP - 255
EP - 259
JO - Gene Expression Patterns
JF - Gene Expression Patterns
IS - 3
ER -