Binding Interactions of Dopamine and Apomorphine in D2High and D2Low States of Human Dopamine D2 Receptor Using Computational and Experimental Techniques

Serdar Durdagi; Ramin Ekhteiari Salmas; Matthias Stein; Mine Yurtsever; Philip Seeman

doi:10.1021/acschemneuro.5b00271

Binding Interactions of Dopamine and Apomorphine in D2High and D2Low States of Human Dopamine D2 Receptor Using Computational and Experimental Techniques

Serdar Durdagi, Ramin Ekhteiari Salmas, Matthias Stein, Mine Yurtsever, Philip Seeman

Chemistry

Research output: Contribution to journal › Article › peer-review

39 Citations (Scopus)

Original language	English
Pages (from-to)	185-195
Journal	Acs chemical neuroscience
Volume	7
Issue number	2
DOIs	https://doi.org/10.1021/acschemneuro.5b00271
Publication status	Published - Feb 2016

Keywords

Dopamine D2 receptor
protein engineering
molecular docking
D2High and D2Low states of dopamine
GPCR dimerization

Access to Document

10.1021/acschemneuro.5b00271

Cite this

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title = "Binding Interactions of Dopamine and Apomorphine in D2High and D2Low States of Human Dopamine D2 Receptor Using Computational and Experimental Techniques",

keywords = "Dopamine D2 receptor, protein engineering, molecular docking, D2High and D2Low states of dopamine, GPCR dimerization",

author = "Serdar Durdagi and Salmas, {Ramin Ekhteiari} and Matthias Stein and Mine Yurtsever and Philip Seeman",

year = "2016",

month = feb,

doi = "10.1021/acschemneuro.5b00271",

language = "English",

volume = "7",

pages = "185--195",

journal = "Acs chemical neuroscience",

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AU - Durdagi, Serdar

AU - Salmas, Ramin Ekhteiari

AU - Stein, Matthias

AU - Yurtsever, Mine

AU - Seeman, Philip

PY - 2016/2

Y1 - 2016/2

KW - Dopamine D2 receptor

KW - protein engineering

KW - molecular docking

KW - D2High and D2Low states of dopamine

KW - GPCR dimerization

U2 - 10.1021/acschemneuro.5b00271

DO - 10.1021/acschemneuro.5b00271

M3 - Article

SN - 1948-7193

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SP - 185

EP - 195

JO - Acs chemical neuroscience

JF - Acs chemical neuroscience

IS - 2

ER -