Biocompatibility of mannan nanogel--safe interaction with plasma proteins

Sílvia A Ferreira; Cecilia Oslakovic; Risto Cukalevski; Birgitta Frohm; Björn Dahlbäck; Sara Linse; Francisco M Gama; Tommy Cedervall

doi:10.1016/j.bbagen.2012.04.015

Biocompatibility of mannan nanogel--safe interaction with plasma proteins

Sílvia A Ferreira, Cecilia Oslakovic, Risto Cukalevski, Birgitta Frohm, Björn Dahlbäck, Sara Linse, Francisco M Gama, Tommy Cedervall

Centre for Craniofacial & Regenerative Biology

Research output: Contribution to journal › Article › peer-review

29 Citations (Scopus)

Abstract

Self-assembled mannan nanogels are designed to provide a therapeutic or vaccine delivery platform based on the bioactive properties of mannan to target mannose receptor expressed on the surface of antigen-presenting cells, combined with the performance of nanogels as carriers of biologically active agents.

Original language	English
Pages (from-to)	1043-51
Number of pages	9
Journal	Biochimica et Biophysica Acta
Volume	1820
Issue number	7
DOIs	https://doi.org/10.1016/j.bbagen.2012.04.015
Publication status	Published - Jul 2012

Keywords

Amyloid beta-Peptides
Antigen-Presenting Cells
Apolipoprotein A-I
Blood Coagulation
Blood Proteins
Chromatography, Gel
Circular Dichroism
Humans
Mannans
Materials Testing
Polyethylene Glycols
Polyethyleneimine
Serum Albumin
Spectrometry, Fluorescence
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Thiazoles
Thrombin
beta 2-Microglobulin

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.bbagen.2012.04.015

Cite this

@article{250c316807e645aab4db4a53a8242729,

title = "Biocompatibility of mannan nanogel--safe interaction with plasma proteins",

abstract = "Self-assembled mannan nanogels are designed to provide a therapeutic or vaccine delivery platform based on the bioactive properties of mannan to target mannose receptor expressed on the surface of antigen-presenting cells, combined with the performance of nanogels as carriers of biologically active agents.",

keywords = "Amyloid beta-Peptides, Antigen-Presenting Cells, Apolipoprotein A-I, Blood Coagulation, Blood Proteins, Chromatography, Gel, Circular Dichroism, Humans, Mannans, Materials Testing, Polyethylene Glycols, Polyethyleneimine, Serum Albumin, Spectrometry, Fluorescence, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Thiazoles, Thrombin, beta 2-Microglobulin",

author = "Ferreira, {S{\'i}lvia A} and Cecilia Oslakovic and Risto Cukalevski and Birgitta Frohm and Bj{\"o}rn Dahlb{\"a}ck and Sara Linse and Gama, {Francisco M} and Tommy Cedervall",

year = "2012",

month = jul,

doi = "10.1016/j.bbagen.2012.04.015",

language = "English",

volume = "1820",

pages = "1043--51",

journal = "Biochimica et Biophysica Acta",

issn = "0006-3002",

publisher = "Elsevier",

number = "7",

}

TY - JOUR

T1 - Biocompatibility of mannan nanogel--safe interaction with plasma proteins

AU - Ferreira, Sílvia A

AU - Oslakovic, Cecilia

AU - Cukalevski, Risto

AU - Frohm, Birgitta

AU - Dahlbäck, Björn

AU - Linse, Sara

AU - Gama, Francisco M

AU - Cedervall, Tommy

PY - 2012/7

Y1 - 2012/7

N2 - Self-assembled mannan nanogels are designed to provide a therapeutic or vaccine delivery platform based on the bioactive properties of mannan to target mannose receptor expressed on the surface of antigen-presenting cells, combined with the performance of nanogels as carriers of biologically active agents.

AB - Self-assembled mannan nanogels are designed to provide a therapeutic or vaccine delivery platform based on the bioactive properties of mannan to target mannose receptor expressed on the surface of antigen-presenting cells, combined with the performance of nanogels as carriers of biologically active agents.

KW - Amyloid beta-Peptides

KW - Antigen-Presenting Cells

KW - Apolipoprotein A-I

KW - Blood Coagulation

KW - Blood Proteins

KW - Chromatography, Gel

KW - Circular Dichroism

KW - Humans

KW - Mannans

KW - Materials Testing

KW - Polyethylene Glycols

KW - Polyethyleneimine

KW - Serum Albumin

KW - Spectrometry, Fluorescence

KW - Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

KW - Thiazoles

KW - Thrombin

KW - beta 2-Microglobulin

U2 - 10.1016/j.bbagen.2012.04.015

DO - 10.1016/j.bbagen.2012.04.015

M3 - Article

C2 - 22554917

SN - 0006-3002

VL - 1820

SP - 1043

EP - 1051

JO - Biochimica et Biophysica Acta

JF - Biochimica et Biophysica Acta

IS - 7

ER -

Biocompatibility of mannan nanogel--safe interaction with plasma proteins

Abstract

Keywords

UN SDGs

Access to Document

Fingerprint

Cite this