Boys do it the right way: sex-dependent amygdala lateralization during face processing in adolescents

S Schneider; J Peters; U Bromberg; S Brassen; M M Menz; S F Miedl; E Loth; T Banaschewski; A Barbot; G Barker; P J Conrod; J W Dalley; H Flor; J Gallinat; H Garavan; A Heinz; B Itterman; C Mallik; K Mann; Eric Artiges; T Paus; J-B Poline; M Rietschel; L Reed; M N Smolka; R Spanagel; C Speiser; A Ströhle; M Struve; G Schumann; C Büchel; IMAGEN Consortium

doi:10.1016/j.neuroimage.2011.02.019

Boys do it the right way: sex-dependent amygdala lateralization during face processing in adolescents

S Schneider, J Peters, U Bromberg, S Brassen, M M Menz, S F Miedl, E Loth, T Banaschewski, A Barbot, G Barker, P J Conrod, J W Dalley, H Flor, J Gallinat, H Garavan, A Heinz, B Itterman, C Mallik, K Mann, Eric ArtigesT Paus, J-B Poline, M Rietschel, L Reed, M N Smolka, R Spanagel, C Speiser, A Ströhle, M Struve, G Schumann, C Büchel, IMAGEN Consortium

UKE University Medical Center Hamburg-Eppendorf

Research output: Contribution to journal › Article › peer-review

68 Citations (Scopus)

Abstract

Previous studies have observed a sex-dependent lateralization of amygdala activation related to emotional memory. Specifically, it was shown that the activity of the right amygdala correlates significantly stronger with memory for images judged as arousing in men than in women, and that there is a significantly stronger relationship in women than in men between activity of the left amygdala and memory for arousing images. Using a large sample of 235 male adolescents and 235 females matched for age and handedness, we investigated the sex-specific lateralization of amygdala activation during an emotional face perception fMRI task. Performing a formal sex by hemisphere analysis, we observed in males a significantly stronger right amygdala activation as compared to females. Our results indicate that adolescents display a sex-dependent lateralization of amygdala activation that is also present in basic processes of emotional perception. This finding suggests a sex-dependent development of human emotion processing and may further implicate possible etiological pathways for mental disorders most frequent in adolescent males (i.e., conduct disorder).

Original language	English
Article number	N/A
Pages (from-to)	1847 - 1853
Number of pages	7
Journal	NeuroImage
Volume	56
Issue number	3
DOIs	https://doi.org/10.1016/j.neuroimage.2011.02.019
Publication status	Published - 1 Jun 2011

Keywords

Adolescent
Amygdala
Anger
Facial Expression
Female
Functional Laterality
Humans
Image Processing, Computer-Assisted
Magnetic Resonance Imaging
Male
Psychomotor Performance
Recognition (Psychology)
Sex Characteristics

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Schneider, S., Peters, J., Bromberg, U., Brassen, S., Menz, M. M., Miedl, S. F., Loth, E., Banaschewski, T., Barbot, A., Barker, G., Conrod, P. J., Dalley, J. W., Flor, H., Gallinat, J., Garavan, H., Heinz, A., Itterman, B., Mallik, C., Mann, K., ... IMAGEN Consortium (2011). Boys do it the right way: sex-dependent amygdala lateralization during face processing in adolescents. NeuroImage, 56(3), 1847 - 1853. Article N/A. https://doi.org/10.1016/j.neuroimage.2011.02.019

@article{5c95e2394c964acebafcbd68ac56f5d5,

title = "Boys do it the right way: sex-dependent amygdala lateralization during face processing in adolescents",

abstract = "Previous studies have observed a sex-dependent lateralization of amygdala activation related to emotional memory. Specifically, it was shown that the activity of the right amygdala correlates significantly stronger with memory for images judged as arousing in men than in women, and that there is a significantly stronger relationship in women than in men between activity of the left amygdala and memory for arousing images. Using a large sample of 235 male adolescents and 235 females matched for age and handedness, we investigated the sex-specific lateralization of amygdala activation during an emotional face perception fMRI task. Performing a formal sex by hemisphere analysis, we observed in males a significantly stronger right amygdala activation as compared to females. Our results indicate that adolescents display a sex-dependent lateralization of amygdala activation that is also present in basic processes of emotional perception. This finding suggests a sex-dependent development of human emotion processing and may further implicate possible etiological pathways for mental disorders most frequent in adolescent males (i.e., conduct disorder).",

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author = "S Schneider and J Peters and U Bromberg and S Brassen and Menz, {M M} and Miedl, {S F} and E Loth and T Banaschewski and A Barbot and G Barker and Conrod, {P J} and Dalley, {J W} and H Flor and J Gallinat and H Garavan and A Heinz and B Itterman and C Mallik and K Mann and Eric Artiges and T Paus and J-B Poline and M Rietschel and L Reed and Smolka, {M N} and R Spanagel and C Speiser and A Str{\"o}hle and M Struve and G Schumann and C B{\"u}chel and {IMAGEN Consortium} and Sylvane Desrivieres",

year = "2011",

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doi = "10.1016/j.neuroimage.2011.02.019",

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Schneider, S, Peters, J, Bromberg, U, Brassen, S, Menz, MM, Miedl, SF, Loth, E, Banaschewski, T, Barbot, A, Barker, G , Conrod, PJ, Dalley, JW, Flor, H, Gallinat, J, Garavan, H, Heinz, A, Itterman, B, Mallik, C, Mann, K, Artiges, E, Paus, T, Poline, J-B, Rietschel, M, Reed, L, Smolka, MN, Spanagel, R, Speiser, C, Ströhle, A, Struve, M, Schumann, G, Büchel, C & IMAGEN Consortium 2011, 'Boys do it the right way: sex-dependent amygdala lateralization during face processing in adolescents', NeuroImage, vol. 56, no. 3, N/A, pp. 1847 - 1853. https://doi.org/10.1016/j.neuroimage.2011.02.019

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T2 - sex-dependent amygdala lateralization during face processing in adolescents

AU - Schneider, S

AU - Peters, J

AU - Bromberg, U

AU - Brassen, S

AU - Menz, M M

AU - Miedl, S F

AU - Loth, E

AU - Banaschewski, T

AU - Barbot, A

AU - Barker, G

AU - Conrod, P J

AU - Dalley, J W

AU - Flor, H

AU - Gallinat, J

AU - Garavan, H

AU - Heinz, A

AU - Itterman, B

AU - Mallik, C

AU - Mann, K

AU - Artiges, Eric

AU - Paus, T

AU - Poline, J-B

AU - Rietschel, M

AU - Reed, L

AU - Smolka, M N

AU - Spanagel, R

AU - Speiser, C

AU - Ströhle, A

AU - Struve, M

AU - Schumann, G

AU - Büchel, C

AU - IMAGEN Consortium

AU - Desrivieres, Sylvane

PY - 2011/6/1

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N2 - Previous studies have observed a sex-dependent lateralization of amygdala activation related to emotional memory. Specifically, it was shown that the activity of the right amygdala correlates significantly stronger with memory for images judged as arousing in men than in women, and that there is a significantly stronger relationship in women than in men between activity of the left amygdala and memory for arousing images. Using a large sample of 235 male adolescents and 235 females matched for age and handedness, we investigated the sex-specific lateralization of amygdala activation during an emotional face perception fMRI task. Performing a formal sex by hemisphere analysis, we observed in males a significantly stronger right amygdala activation as compared to females. Our results indicate that adolescents display a sex-dependent lateralization of amygdala activation that is also present in basic processes of emotional perception. This finding suggests a sex-dependent development of human emotion processing and may further implicate possible etiological pathways for mental disorders most frequent in adolescent males (i.e., conduct disorder).

AB - Previous studies have observed a sex-dependent lateralization of amygdala activation related to emotional memory. Specifically, it was shown that the activity of the right amygdala correlates significantly stronger with memory for images judged as arousing in men than in women, and that there is a significantly stronger relationship in women than in men between activity of the left amygdala and memory for arousing images. Using a large sample of 235 male adolescents and 235 females matched for age and handedness, we investigated the sex-specific lateralization of amygdala activation during an emotional face perception fMRI task. Performing a formal sex by hemisphere analysis, we observed in males a significantly stronger right amygdala activation as compared to females. Our results indicate that adolescents display a sex-dependent lateralization of amygdala activation that is also present in basic processes of emotional perception. This finding suggests a sex-dependent development of human emotion processing and may further implicate possible etiological pathways for mental disorders most frequent in adolescent males (i.e., conduct disorder).

KW - Adolescent

KW - Amygdala

KW - Anger

KW - Facial Expression

KW - Female

KW - Functional Laterality

KW - Humans

KW - Image Processing, Computer-Assisted

KW - Magnetic Resonance Imaging

KW - Male

KW - Psychomotor Performance

KW - Recognition (Psychology)

KW - Sex Characteristics

U2 - 10.1016/j.neuroimage.2011.02.019

DO - 10.1016/j.neuroimage.2011.02.019

M3 - Article

C2 - 21316467

SN - 1095-9572

VL - 56

SP - 1847

EP - 1853

JO - NeuroImage

JF - NeuroImage

IS - 3

M1 - N/A

ER -

Boys do it the right way: sex-dependent amygdala lateralization during face processing in adolescents

Abstract

Keywords

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