Can nasal ischaemia predict proliferative retinopathy in type 2 diabetes?

G C Vafidis, J V Arnold, A M Hamilton

Research output: Contribution to journalMeeting abstract

Abstract

Purpose: To define arc-pattern nasal retinal ischaemia on fluorescein angiography (FFA) and explore its temporal relationship with development of proliferative diabetic retinopathy (PDR) Methods: We analysed FFA of 30 Type 2 diabetic eyes with peripheral retinal ischaemia in 4 quadrants. Areas of ischaemia were identified when crossing arterioles and venules stained in late-venous phase angiograms. Tracing disc and main vessels on to overlaid acetate sheets created a retinal montage of each eye and the posterior limit of vessel staining was marked on the montage. This produced a centripetal arc-pattern around the disc in the nasal retina. The anterior limit of the arc was marked if present. The best fit 'centre' of the posterior arc was determined by comparison with overlaid concentric circles and distance from arc to nasal disc was measured in disc diameters (dd). The onset of subsequent PDR in these eyes was determined from clinical records. Results: All eyes that developed PDR within a year of the FFA date (n=8) had nasal retinal ischaemia almost up to (
Original languageEnglish
Pages (from-to)3860
Number of pages1
JournalInvestigative Ophthalmology & Visual Science
Volume43
Publication statusPublished - 2002
EventAnnual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology - FT LAUDERDALE, FLORIDA
Duration: 1 Jan 2004 → …

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