TY - JOUR
T1 - Case report: 'Photodynamics of Subependymal Giant Cell Astrocytoma with 5-Aminolevulinic acid'
AU - Ghani, Imran
AU - Patel, Sabina
AU - Ghimire, Prajwal
AU - Bodi, Istvan
AU - Bhangoo, Ranjeev
AU - Vergani, Francesco
AU - Ashkan, Keyoumars
AU - Lavrador, Jose Pedro
N1 - Publisher Copyright:
2023 Ghani, Patel, Ghimire, Bodi, Bhangoo, Vergani, Ashkan and Lavrador.
PY - 2023/1/6
Y1 - 2023/1/6
N2 - Subependymal Giant Cell Astrocytoma (SEGA) is a common diagnosis in patients with Tuberous Sclerosis. Although surgical treatment is often required, resection may entail a significant risk for cognitive function given the anatomical relation with critical structures such as the fornices and subgenual area. Therefore, target subtotal resections using minimal invasive approaches focused in the higher metabolic areas are valuable options to preserve quality of life while addressing specific problems caused by the tumor, such as hydrocephalus or progressive growth of a specific component of the tumor. In this report, the authors explore the potential role of 5-ALA in the identification of highly metabolic areas during SEGA resection in the context of minimal invasive approaches.
AB - Subependymal Giant Cell Astrocytoma (SEGA) is a common diagnosis in patients with Tuberous Sclerosis. Although surgical treatment is often required, resection may entail a significant risk for cognitive function given the anatomical relation with critical structures such as the fornices and subgenual area. Therefore, target subtotal resections using minimal invasive approaches focused in the higher metabolic areas are valuable options to preserve quality of life while addressing specific problems caused by the tumor, such as hydrocephalus or progressive growth of a specific component of the tumor. In this report, the authors explore the potential role of 5-ALA in the identification of highly metabolic areas during SEGA resection in the context of minimal invasive approaches.
UR - http://www.scopus.com/inward/record.url?scp=85146612803&partnerID=8YFLogxK
U2 - 10.3389/fsurg.2022.1065979
DO - 10.3389/fsurg.2022.1065979
M3 - Article
C2 - 36684213
SN - 2296-875X
VL - 9
SP - 1065979
JO - Frontiers in Surgery
JF - Frontiers in Surgery
M1 - 1065979
ER -