@inbook{a7c4ae497c324a5a8a998492ea258dd2,
title = "CHAPTER 3: Use of Molecular Modelling Techniques in Antibody-Drug Conjugate (ADC) Payload Discovery and Development",
abstract = "Computational drug discovery efforts have, historically, concentrated on molecular docking calculations, focusing on a {"}lock-and-key{"} theory, whereby a rigid ligand structure is fitted in its lowest energy minimum conformation into a rigid receptor followed by calculation of affinity. Potential hits are then ranked using a docking {"}score{"}.",
author = "Jackson, {Paul J.M.} and Thurston, {David E.}",
year = "2019",
month = jan,
day = "1",
doi = "10.1039/9781788012898-00057",
language = "English",
series = "RSC Drug Discovery Series",
publisher = "Royal Society of Chemistry",
number = "71",
pages = "57--72",
editor = "Thurston, {David E.} and Jackson, {Paul J. M.}",
booktitle = "Therapies for Retinal Degeneration",
address = "United Kingdom",
edition = "71",
}