TY - JOUR
T1 - Comparison of Y-chromosome haplotypes in three racial groups and the possibility of predicting ethnic origin
AU - Syndercombe Court, D.
AU - Ballard, D.
AU - Phillips, Chris
AU - Revoir, A.
AU - Robson, C.
AU - Thacker, C.
N1 - Progress in Forensic Genetics 9. Proceedings from the 19th International ISFG Congress held in Munster, Germany between 28 August and 1 September 2001
PY - 2003/1
Y1 - 2003/1
N2 - Currently, most STRs found on the Y-chromosome exhibit much lower levels of polymorphism when compared to autosomal STRs. However, unlike autosomal STRs, they often show marked differences in allele frequency distributions between racial groups. Two hundred unrelated males from each of the three principal ethnic groupings within the UK were typed for 11 loci and used to build a predictive model for those classifications. An additional 50 individuals from each group were used in a blind trial to validate the model and the utility of the assignments assessed by calculating likelihood ratios. Use of a haplotype consisting of only three Y-chromosome STRs correctly identified 81%, 96% and 70% of individuals who defined themselves as white, black or South Asian.
AB - Currently, most STRs found on the Y-chromosome exhibit much lower levels of polymorphism when compared to autosomal STRs. However, unlike autosomal STRs, they often show marked differences in allele frequency distributions between racial groups. Two hundred unrelated males from each of the three principal ethnic groupings within the UK were typed for 11 loci and used to build a predictive model for those classifications. An additional 50 individuals from each group were used in a blind trial to validate the model and the utility of the assignments assessed by calculating likelihood ratios. Use of a haplotype consisting of only three Y-chromosome STRs correctly identified 81%, 96% and 70% of individuals who defined themselves as white, black or South Asian.
U2 - 10.1016/S0531-5131(02)00229-7
DO - 10.1016/S0531-5131(02)00229-7
M3 - Article
SN - 0531-5131
VL - 1239
SP - 67
EP - 69
JO - International Congress Series
JF - International Congress Series
ER -