Deep and surface hemodynamic signal from functional time resolved transcranial near infrared spectroscopy compared to skin flowmotion

Federico Aletti; Rebecca Re; Vincenzo Pace; Davide Contini; Erika Molteni; Sergio Cerutti; Anna Maria Bianchi; Alessandro Torricelli; Lorenzo Spinelli; Rinaldo Cubeddu; Giuseppe Baselli

doi:10.1016/j.compbiomed.2011.06.001

Deep and surface hemodynamic signal from functional time resolved transcranial near infrared spectroscopy compared to skin flowmotion

Federico Aletti, Rebecca Re, Vincenzo Pace, Davide Contini, Erika Molteni, Sergio Cerutti, Anna Maria Bianchi, Alessandro Torricelli, Lorenzo Spinelli, Rinaldo Cubeddu, Giuseppe Baselli

Biomedical Engineering Department

Dipartimento di Bioingegneria IIT Unit, Politecnico di Milano, Milan, Italy. [email protected]

Research output: Contribution to journal › Article › peer-review

42 Citations (Scopus)

Abstract

The potential disturbance in the prefrontal cortex hemodynamic signal measured by functional near infrared spectroscopy (NIRS), due to forehead skin flowmotion, detected by laser Doppler flowmetry, was investigated by a standard protocol of hemodynamic challenge by Valsalva maneuver, aimed at assessing and disentangling local regulatory responses in skin vasomotion and in cerebral perfusion in presence of a strong systemic drive, and to quantify the common information in the two signals. The deep cortical NIRS signal did not appear to be affected by surface vasomotor activity, and autoregulation dynamics were dominant with respect to autonomic control of circulation.

Original language	English
Pages (from-to)	282-9
Number of pages	8
Journal	Computers in Biology and Medicine
Volume	42
Issue number	3
DOIs	https://doi.org/10.1016/j.compbiomed.2011.06.001
Publication status	Published - Mar 2012

Keywords

Cerebrovascular Circulation
Computer Simulation
Forehead/blood supply
Hemoglobins/analysis
Humans
Laser-Doppler Flowmetry/methods
Models, Cardiovascular
Phantoms, Imaging
Prefrontal Cortex/blood supply
Signal Processing, Computer-Assisted
Skin/blood supply
Spectroscopy, Near-Infrared/methods
Valsalva Maneuver

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10.1016/j.compbiomed.2011.06.001

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Aletti, F., Re, R., Pace, V., Contini, D., Molteni, E., Cerutti, S., Maria Bianchi, A., Torricelli, A., Spinelli, L., Cubeddu, R., & Baselli, G. (2012). Deep and surface hemodynamic signal from functional time resolved transcranial near infrared spectroscopy compared to skin flowmotion. Computers in Biology and Medicine, 42(3), 282-9. https://doi.org/10.1016/j.compbiomed.2011.06.001

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title = "Deep and surface hemodynamic signal from functional time resolved transcranial near infrared spectroscopy compared to skin flowmotion",

abstract = "The potential disturbance in the prefrontal cortex hemodynamic signal measured by functional near infrared spectroscopy (NIRS), due to forehead skin flowmotion, detected by laser Doppler flowmetry, was investigated by a standard protocol of hemodynamic challenge by Valsalva maneuver, aimed at assessing and disentangling local regulatory responses in skin vasomotion and in cerebral perfusion in presence of a strong systemic drive, and to quantify the common information in the two signals. The deep cortical NIRS signal did not appear to be affected by surface vasomotor activity, and autoregulation dynamics were dominant with respect to autonomic control of circulation.",

keywords = "Cerebrovascular Circulation, Computer Simulation, Forehead/blood supply, Hemoglobins/analysis, Humans, Laser-Doppler Flowmetry/methods, Models, Cardiovascular, Phantoms, Imaging, Prefrontal Cortex/blood supply, Signal Processing, Computer-Assisted, Skin/blood supply, Spectroscopy, Near-Infrared/methods, Valsalva Maneuver",

author = "Federico Aletti and Rebecca Re and Vincenzo Pace and Davide Contini and Erika Molteni and Sergio Cerutti and {Maria Bianchi}, Anna and Alessandro Torricelli and Lorenzo Spinelli and Rinaldo Cubeddu and Giuseppe Baselli",

year = "2012",

month = mar,

doi = "10.1016/j.compbiomed.2011.06.001",

language = "English",

volume = "42",

pages = "282--9",

journal = "Computers in Biology and Medicine",

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Aletti, F, Re, R, Pace, V, Contini, D, Molteni, E, Cerutti, S, Maria Bianchi, A, Torricelli, A, Spinelli, L, Cubeddu, R & Baselli, G 2012, 'Deep and surface hemodynamic signal from functional time resolved transcranial near infrared spectroscopy compared to skin flowmotion', Computers in Biology and Medicine, vol. 42, no. 3, pp. 282-9. https://doi.org/10.1016/j.compbiomed.2011.06.001

TY - JOUR

T1 - Deep and surface hemodynamic signal from functional time resolved transcranial near infrared spectroscopy compared to skin flowmotion

AU - Aletti, Federico

AU - Re, Rebecca

AU - Pace, Vincenzo

AU - Contini, Davide

AU - Molteni, Erika

AU - Cerutti, Sergio

AU - Maria Bianchi, Anna

AU - Torricelli, Alessandro

AU - Spinelli, Lorenzo

AU - Cubeddu, Rinaldo

AU - Baselli, Giuseppe

PY - 2012/3

Y1 - 2012/3

N2 - The potential disturbance in the prefrontal cortex hemodynamic signal measured by functional near infrared spectroscopy (NIRS), due to forehead skin flowmotion, detected by laser Doppler flowmetry, was investigated by a standard protocol of hemodynamic challenge by Valsalva maneuver, aimed at assessing and disentangling local regulatory responses in skin vasomotion and in cerebral perfusion in presence of a strong systemic drive, and to quantify the common information in the two signals. The deep cortical NIRS signal did not appear to be affected by surface vasomotor activity, and autoregulation dynamics were dominant with respect to autonomic control of circulation.

AB - The potential disturbance in the prefrontal cortex hemodynamic signal measured by functional near infrared spectroscopy (NIRS), due to forehead skin flowmotion, detected by laser Doppler flowmetry, was investigated by a standard protocol of hemodynamic challenge by Valsalva maneuver, aimed at assessing and disentangling local regulatory responses in skin vasomotion and in cerebral perfusion in presence of a strong systemic drive, and to quantify the common information in the two signals. The deep cortical NIRS signal did not appear to be affected by surface vasomotor activity, and autoregulation dynamics were dominant with respect to autonomic control of circulation.

KW - Cerebrovascular Circulation

KW - Computer Simulation

KW - Forehead/blood supply

KW - Hemoglobins/analysis

KW - Humans

KW - Laser-Doppler Flowmetry/methods

KW - Models, Cardiovascular

KW - Phantoms, Imaging

KW - Prefrontal Cortex/blood supply

KW - Signal Processing, Computer-Assisted

KW - Skin/blood supply

KW - Spectroscopy, Near-Infrared/methods

KW - Valsalva Maneuver

U2 - 10.1016/j.compbiomed.2011.06.001

DO - 10.1016/j.compbiomed.2011.06.001

M3 - Article

C2 - 21742320

SN - 0010-4825

VL - 42

SP - 282

EP - 289

JO - Computers in Biology and Medicine

JF - Computers in Biology and Medicine

IS - 3

ER -

Deep and surface hemodynamic signal from functional time resolved transcranial near infrared spectroscopy compared to skin flowmotion

Abstract

Keywords

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