Development and function of tissue resident macrophages in mice

Katrin Kierdorf; Marco Prinz; Frederic Geissmann; Elisa Gomez Perdiguero

doi:10.1016/j.smim.2016.03.017

Development and function of tissue resident macrophages in mice

Katrin Kierdorf, Marco Prinz, Frederic Geissmann, Elisa Gomez Perdiguero

Research output: Contribution to journal › Article › peer-review

75 Citations (Scopus)

Abstract

Macrophages are important for tissue development, homeostasis as well as immune response upon injury or infection. For a long time they were only seen as one uniform group of phagocytes with a common origin and similar functions. However, this view has been challenged in the last decade and revealed a complex diversity of tissue resident macrophages. Here, we want to present the current view on macrophage development and tissue specification and we will discuss differences as well as common patterns between heterogeneous macrophage subpopulations.

Original language	English
Journal	Seminars in Immunology
Early online date	29 Mar 2016
DOIs	https://doi.org/10.1016/j.smim.2016.03.017
Publication status	E-pub ahead of print - 29 Mar 2016

Keywords

Macrophage
Erythro-myeloid progenitor
Tissue specification
Pulse labeling models
Mononuclear phagocytes

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10.1016/j.smim.2016.03.017

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title = "Development and function of tissue resident macrophages in mice",

abstract = "Macrophages are important for tissue development, homeostasis as well as immune response upon injury or infection. For a long time they were only seen as one uniform group of phagocytes with a common origin and similar functions. However, this view has been challenged in the last decade and revealed a complex diversity of tissue resident macrophages. Here, we want to present the current view on macrophage development and tissue specification and we will discuss differences as well as common patterns between heterogeneous macrophage subpopulations.",

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KW - Macrophage

KW - Erythro-myeloid progenitor

KW - Tissue specification

KW - Pulse labeling models

KW - Mononuclear phagocytes

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M3 - Article

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JO - Seminars in Immunology

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Development and function of tissue resident macrophages in mice

Abstract

Keywords

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