TY - JOUR
T1 - Dithiocarbamate complexes as radiopharmaceuticals for medical imaging
AU - Berry, David J.
AU - de Rosales, Rafael Torres Martin
AU - Charoenphun, Putthiporn
AU - Blower, Philip J.
PY - 2012/10
Y1 - 2012/10
N2 - Over the past 30 years dithiocarbamate ligands have found application in radiopharmaceutical metal-ligand complexes to image a range of disease states. The vast majority of research and applications, and the widest range of complex structures, have involved radionuclides of technetium and rhenium. Considering the extent of coordination chemistry of dithiocarbamate ligands described elsewhere in this issue, the extent of radiopharmaceutical application with metallic radionuclides is surprisingly narrow. Here we summarise the types of radiopharmaceutical complexes studied and the uses, and potential uses, to which they have been put in nuclear medicine.
AB - Over the past 30 years dithiocarbamate ligands have found application in radiopharmaceutical metal-ligand complexes to image a range of disease states. The vast majority of research and applications, and the widest range of complex structures, have involved radionuclides of technetium and rhenium. Considering the extent of coordination chemistry of dithiocarbamate ligands described elsewhere in this issue, the extent of radiopharmaceutical application with metallic radionuclides is surprisingly narrow. Here we summarise the types of radiopharmaceutical complexes studied and the uses, and potential uses, to which they have been put in nuclear medicine.
U2 - 10.2174/138955712802762112
DO - 10.2174/138955712802762112
M3 - Literature review
SN - 1389-5575
VL - 12
SP - 1174
EP - 1183
JO - MINI-REVIEWS IN MEDICINAL CHEMISTRY
JF - MINI-REVIEWS IN MEDICINAL CHEMISTRY
IS - 12
ER -