TY - JOUR
T1 - Diverging from Nature
T2 - A New Reactivity for Molecular Synthesizers
AU - McTernan, Charlie T.
N1 - Publisher Copyright:
© 2020 Elsevier Inc.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/11/5
Y1 - 2020/11/5
N2 - Previous generations of artificial molecular synthesizers, inspired by the ribosome, have depended on amide-bond formation to generate sequence-specific oligomers. Dr. Charlie McTernan discusses how, with Dr. Guillaume De Bo and Prof. David Leigh, he designed and synthesized a carbon–carbon bond-forming molecular machine. This molecular assembler moves along a track while iteratively joining together building blocks to form an oligomer of single sequence with a continuous backbone of carbon–carbon bonds.
AB - Previous generations of artificial molecular synthesizers, inspired by the ribosome, have depended on amide-bond formation to generate sequence-specific oligomers. Dr. Charlie McTernan discusses how, with Dr. Guillaume De Bo and Prof. David Leigh, he designed and synthesized a carbon–carbon bond-forming molecular machine. This molecular assembler moves along a track while iteratively joining together building blocks to form an oligomer of single sequence with a continuous backbone of carbon–carbon bonds.
UR - http://www.scopus.com/inward/record.url?scp=85094834183&partnerID=8YFLogxK
U2 - 10.1016/j.chempr.2020.10.004
DO - 10.1016/j.chempr.2020.10.004
M3 - Article
AN - SCOPUS:85094834183
SN - 2451-9308
VL - 6
SP - 2862
EP - 2864
JO - Chem
JF - Chem
IS - 11
ER -