Projects per year
Abstract
Two genetic findings from twin research have far-reaching implications for understanding individual differences in the development of brain function as indexed by general cognitive ability (g, aka intelligence): (1) The same genes affect g throughout development, even though (2) heritability increases. It is now possible to test these hypotheses using DNA alone. From 1.7 million DNA markers and g scores at ages 7 and 12 on 2875 children, the DNA genetic correlation from age 7 to 12 was 0.73, highly similar to the genetic correlation of 0.75 estimated from 6702 pairs of twins from the same sample. DNA-estimated heritabilities increased from 0.26 at age 7 to 0.45 at age 12; twin-estimated heritabilities also increased from 0.35 to 0.48. These DNA results confirm the results of twin studies indicating strong genetic stability but increasing heritability for g, despite mean changes in brain structure and function from childhood to adolescence.
Original language | English |
---|---|
Pages (from-to) | 380-384 |
Number of pages | 5 |
Journal | Molecular Psychiatry |
Volume | 19 |
Issue number | 3 |
Early online date | 29 Jan 2013 |
DOIs | |
Publication status | Published - Mar 2014 |
Keywords
- Cognitive development
- Genome-wide complex trait analysis (GCTA)
- Intelligence
- Twins
Fingerprint
Dive into the research topics of 'DNA evidence for strong genetic stability and increasing heritability of intelligence from age 7 to 12'. Together they form a unique fingerprint.Projects
- 6 Finished
-
GHCA: Genetics of High Cognitive Abilities
Plomin, R. (Primary Investigator)
1/04/2012 → 31/03/2017
Project: Research
-
Non-Clinical Research Professorship.
Plomin, R. (Primary Investigator)
1/10/2010 → 30/09/2015
Project: Research
-
Origins of learning difficulties and behaviour problems: from behavioural genetics to behavioural genomics
Plomin, R. (Primary Investigator)
1/10/2010 → 30/09/2015
Project: Research