Dopamine and the biology and course of treatment resistance

Arsime Demjaha; Oliver D. Howes

doi:10.1007/978-3-642-45257-4_3

Dopamine and the biology and course of treatment resistance

Arsime Demjaha^*, Oliver D. Howes

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

1 Citation (Scopus)

Abstract

The onset and course of schizophrenia, like many complex conditions, is influenced both by biological and psychosocial factors. The biological precursors of non-response to treatment in schizophrenia are as yet unknown, but for example, emerging functional imagining work suggests that there may be underlying differences in neurotransmitter patterns in people who have not responded to standard treatment compared to those who do. Long term epidemiological follow up studies may also give clues as to where to direct resources for best outcomes. This chapter will address both the biological and epidemiological associations of poor outcome and response to treatment in schizophrenia, preparing the ground for secondary preventative work in the future.

Original language	English
Title of host publication	Treatment-Refractory Schizophrenia: A Clinical Conundrum
Publisher	Springer Berlin Heidelberg
Pages	31-44
Number of pages	14
ISBN (Electronic)	9783642452574
ISBN (Print)	9783642452567
DOIs	https://doi.org/10.1007/978-3-642-45257-4_3
Publication status	Published - 1 Jan 2014

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Dopamine and the biology and course of treatment resistance

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