Early Results of Fenestrated Endovascular Repair of Juxtarenal Aortic Aneurysms in the United Kingdom

G. Ambler; J. R. Boyle; C. Cousins; P. D. Hayes; T. Metha; T. C. See; K. Varty; A. Winterbottom; D. J. Adam; A. W. Bradbury; M. J. Clarke; R. Jackson; J. D. Rose; A. Sharif; V. Wealleans; R. Williams; L. Wilson; M. G. Wyatt; I. Ahmed; Rachel Bell; T. W. Carrell; P. Gkoutzios; T. Sabharwal; R. Salter; M. Waltham; C. Bicknell; P. Bourke; N. Cheshire; I. Franklin; A. James; M. P. Jenkins; Mark Tyrrell; C. J. Wilkins; M. Bown; E. Choke; M. McCarthy; R. Sayers; A. Tamberaja; F. Farquharson; F. Serracino-Inglott; M. Davis; G. Hamilton; J. A. Brennan; R. Canavati; R. K. Fisher; R. G. McWilliams; J. B. Naik; Srinivasa Rao Vallabhaneni; J. Hardman; S. Black; British Soc Endovasc Therapy; Global Collaborators Adv Stent

doi:10.1161/CIRCULATIONAHA.111.070334

Early Results of Fenestrated Endovascular Repair of Juxtarenal Aortic Aneurysms in the United Kingdom

G. Ambler, J. R. Boyle, C. Cousins, P. D. Hayes, T. Metha, T. C. See, K. Varty, A. Winterbottom, D. J. Adam, A. W. Bradbury, M. J. Clarke, R. Jackson, J. D. Rose, A. Sharif, V. Wealleans, R. Williams, L. Wilson, M. G. Wyatt, I. Ahmed, Rachel BellT. W. Carrell, P. Gkoutzios, T. Sabharwal, R. Salter, M. Waltham, C. Bicknell, P. Bourke, N. Cheshire, I. Franklin, A. James, M. P. Jenkins, Mark Tyrrell, C. J. Wilkins, M. Bown, E. Choke, M. McCarthy, R. Sayers, A. Tamberaja, F. Farquharson, F. Serracino-Inglott, M. Davis, G. Hamilton, J. A. Brennan, R. Canavati, R. K. Fisher, R. G. McWilliams, J. B. Naik, Srinivasa Rao Vallabhaneni^*, J. Hardman, S. Black, British Soc Endovasc Therapy, Global Collaborators Adv Stent

^*Corresponding author for this work

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Abstract

Background-Fenestrated endovascular repair of abdominal aortic aneurysms has been proposed as an alternative to open surgery for juxtarenal and pararenal abdominal aortic aneurysms. At present, the evidence base for this procedure is predominantly limited to single-center or single-operator series. The aim of this study was to present nationwide early results of fenestrated endovascular repair in the United Kingdom.

Methods and Results-All patients who underwent fenestrated endovascular repair between January 2007 and December 2010 at experienced institutions in the United Kingdom(>10 procedures) were retrospectively studied by use of the GLOBALSTAR database. Site-reported data relating to patient demographics, aneurysm morphology, procedural details, and outcome were recorded. Data from 318 patients were obtained from 14 centers. Primary procedural success was achieved in 99% (316/318); perioperative mortality was 4.1%, and intraoperative target vessel loss was observed in 5 of 889 target vessels (0.6%). The early reintervention (30 days) was 90% (0.02), 86% (0.03), and 70% (0.08) at 1, 2, and 3 years.

Conclusions-In this national sample, fenestrated endovascular repair has been performed with a high degree of technical and clinical success. Late survival and target vessel patency are satisfactory. These results support continued use and evaluation of this technique for juxtarenal aneurysms, but illustrate the need for a more robust evidence base.

Original language	English
Pages (from-to)	2707-2715
Number of pages	9
Journal	Circulation (Baltimore)
Volume	125
Issue number	22
DOIs	https://doi.org/10.1161/CIRCULATIONAHA.111.070334
Publication status	Published - 5 Jun 2012

Keywords

fenestrated endovascular aneurysm repair
juxtarenal aneurysm
target vessel
endovascular aneurysm repair
fenestration
THORACOABDOMINAL ANEURYSMS
REPORTING STANDARDS
STENT
COLLABORATORS
EXPERIENCE

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10.1161/CIRCULATIONAHA.111.070334

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Ambler, G., Boyle, J. R., Cousins, C., Hayes, P. D., Metha, T., See, T. C., Varty, K., Winterbottom, A., Adam, D. J., Bradbury, A. W., Clarke, M. J., Jackson, R., Rose, J. D., Sharif, A., Wealleans, V., Williams, R., Wilson, L., Wyatt, M. G., Ahmed, I., ... Global Collaborators Adv Stent (2012). Early Results of Fenestrated Endovascular Repair of Juxtarenal Aortic Aneurysms in the United Kingdom. Circulation (Baltimore), 125(22), 2707-2715. https://doi.org/10.1161/CIRCULATIONAHA.111.070334

@article{d9fd088029b3489b9b449922312e24de,

title = "Early Results of Fenestrated Endovascular Repair of Juxtarenal Aortic Aneurysms in the United Kingdom",

abstract = "Background-Fenestrated endovascular repair of abdominal aortic aneurysms has been proposed as an alternative to open surgery for juxtarenal and pararenal abdominal aortic aneurysms. At present, the evidence base for this procedure is predominantly limited to single-center or single-operator series. The aim of this study was to present nationwide early results of fenestrated endovascular repair in the United Kingdom. Methods and Results-All patients who underwent fenestrated endovascular repair between January 2007 and December 2010 at experienced institutions in the United Kingdom(>10 procedures) were retrospectively studied by use of the GLOBALSTAR database. Site-reported data relating to patient demographics, aneurysm morphology, procedural details, and outcome were recorded. Data from 318 patients were obtained from 14 centers. Primary procedural success was achieved in 99% (316/318); perioperative mortality was 4.1%, and intraoperative target vessel loss was observed in 5 of 889 target vessels (0.6%). The early reintervention (30 days) was 90% (0.02), 86% (0.03), and 70% (0.08) at 1, 2, and 3 years. Conclusions-In this national sample, fenestrated endovascular repair has been performed with a high degree of technical and clinical success. Late survival and target vessel patency are satisfactory. These results support continued use and evaluation of this technique for juxtarenal aneurysms, but illustrate the need for a more robust evidence base.",

keywords = "fenestrated endovascular aneurysm repair, juxtarenal aneurysm, target vessel, endovascular aneurysm repair, fenestration, THORACOABDOMINAL ANEURYSMS, REPORTING STANDARDS, STENT, COLLABORATORS, EXPERIENCE",

author = "G. Ambler and Boyle, {J. R.} and C. Cousins and Hayes, {P. D.} and T. Metha and See, {T. C.} and K. Varty and A. Winterbottom and Adam, {D. J.} and Bradbury, {A. W.} and Clarke, {M. J.} and R. Jackson and Rose, {J. D.} and A. Sharif and V. Wealleans and R. Williams and L. Wilson and Wyatt, {M. G.} and I. Ahmed and Rachel Bell and Carrell, {T. W.} and P. Gkoutzios and T. Sabharwal and R. Salter and M. Waltham and C. Bicknell and P. Bourke and N. Cheshire and I. Franklin and A. James and Jenkins, {M. P.} and Mark Tyrrell and Wilkins, {C. J.} and M. Bown and E. Choke and M. McCarthy and R. Sayers and A. Tamberaja and F. Farquharson and F. Serracino-Inglott and M. Davis and G. Hamilton and Brennan, {J. A.} and R. Canavati and Fisher, {R. K.} and McWilliams, {R. G.} and Naik, {J. B.} and Vallabhaneni, {Srinivasa Rao} and J. Hardman and S. Black and {British Soc Endovasc Therapy} and {Global Collaborators Adv Stent}",

year = "2012",

month = jun,

day = "5",

doi = "10.1161/CIRCULATIONAHA.111.070334",

language = "English",

volume = "125",

pages = "2707--2715",

journal = "Circulation (Baltimore)",

issn = "0009-7322",

publisher = "American Heart Association, Inc.",

number = "22",

}

Ambler, G, Boyle, JR, Cousins, C, Hayes, PD, Metha, T, See, TC, Varty, K, Winterbottom, A, Adam, DJ, Bradbury, AW, Clarke, MJ, Jackson, R, Rose, JD, Sharif, A, Wealleans, V, Williams, R, Wilson, L, Wyatt, MG, Ahmed, I, Bell, R, Carrell, TW, Gkoutzios, P, Sabharwal, T, Salter, R, Waltham, M, Bicknell, C, Bourke, P, Cheshire, N, Franklin, I, James, A, Jenkins, MP, Tyrrell, M, Wilkins, CJ, Bown, M, Choke, E, McCarthy, M, Sayers, R, Tamberaja, A, Farquharson, F, Serracino-Inglott, F, Davis, M, Hamilton, G, Brennan, JA, Canavati, R, Fisher, RK, McWilliams, RG, Naik, JB, Vallabhaneni, SR, Hardman, J, Black, S, British Soc Endovasc Therapy & Global Collaborators Adv Stent 2012, 'Early Results of Fenestrated Endovascular Repair of Juxtarenal Aortic Aneurysms in the United Kingdom', Circulation (Baltimore), vol. 125, no. 22, pp. 2707-2715. https://doi.org/10.1161/CIRCULATIONAHA.111.070334

TY - JOUR

T1 - Early Results of Fenestrated Endovascular Repair of Juxtarenal Aortic Aneurysms in the United Kingdom

AU - Ambler, G.

AU - Boyle, J. R.

AU - Cousins, C.

AU - Hayes, P. D.

AU - Metha, T.

AU - See, T. C.

AU - Varty, K.

AU - Winterbottom, A.

AU - Adam, D. J.

AU - Bradbury, A. W.

AU - Clarke, M. J.

AU - Jackson, R.

AU - Rose, J. D.

AU - Sharif, A.

AU - Wealleans, V.

AU - Williams, R.

AU - Wilson, L.

AU - Wyatt, M. G.

AU - Ahmed, I.

AU - Bell, Rachel

AU - Carrell, T. W.

AU - Gkoutzios, P.

AU - Sabharwal, T.

AU - Salter, R.

AU - Waltham, M.

AU - Bicknell, C.

AU - Bourke, P.

AU - Cheshire, N.

AU - Franklin, I.

AU - James, A.

AU - Jenkins, M. P.

AU - Tyrrell, Mark

AU - Wilkins, C. J.

AU - Bown, M.

AU - Choke, E.

AU - McCarthy, M.

AU - Sayers, R.

AU - Tamberaja, A.

AU - Farquharson, F.

AU - Serracino-Inglott, F.

AU - Davis, M.

AU - Hamilton, G.

AU - Brennan, J. A.

AU - Canavati, R.

AU - Fisher, R. K.

AU - McWilliams, R. G.

AU - Naik, J. B.

AU - Vallabhaneni, Srinivasa Rao

AU - Hardman, J.

AU - Black, S.

AU - British Soc Endovasc Therapy

AU - Global Collaborators Adv Stent

PY - 2012/6/5

Y1 - 2012/6/5

N2 - Background-Fenestrated endovascular repair of abdominal aortic aneurysms has been proposed as an alternative to open surgery for juxtarenal and pararenal abdominal aortic aneurysms. At present, the evidence base for this procedure is predominantly limited to single-center or single-operator series. The aim of this study was to present nationwide early results of fenestrated endovascular repair in the United Kingdom. Methods and Results-All patients who underwent fenestrated endovascular repair between January 2007 and December 2010 at experienced institutions in the United Kingdom(>10 procedures) were retrospectively studied by use of the GLOBALSTAR database. Site-reported data relating to patient demographics, aneurysm morphology, procedural details, and outcome were recorded. Data from 318 patients were obtained from 14 centers. Primary procedural success was achieved in 99% (316/318); perioperative mortality was 4.1%, and intraoperative target vessel loss was observed in 5 of 889 target vessels (0.6%). The early reintervention (30 days) was 90% (0.02), 86% (0.03), and 70% (0.08) at 1, 2, and 3 years. Conclusions-In this national sample, fenestrated endovascular repair has been performed with a high degree of technical and clinical success. Late survival and target vessel patency are satisfactory. These results support continued use and evaluation of this technique for juxtarenal aneurysms, but illustrate the need for a more robust evidence base.

AB - Background-Fenestrated endovascular repair of abdominal aortic aneurysms has been proposed as an alternative to open surgery for juxtarenal and pararenal abdominal aortic aneurysms. At present, the evidence base for this procedure is predominantly limited to single-center or single-operator series. The aim of this study was to present nationwide early results of fenestrated endovascular repair in the United Kingdom. Methods and Results-All patients who underwent fenestrated endovascular repair between January 2007 and December 2010 at experienced institutions in the United Kingdom(>10 procedures) were retrospectively studied by use of the GLOBALSTAR database. Site-reported data relating to patient demographics, aneurysm morphology, procedural details, and outcome were recorded. Data from 318 patients were obtained from 14 centers. Primary procedural success was achieved in 99% (316/318); perioperative mortality was 4.1%, and intraoperative target vessel loss was observed in 5 of 889 target vessels (0.6%). The early reintervention (30 days) was 90% (0.02), 86% (0.03), and 70% (0.08) at 1, 2, and 3 years. Conclusions-In this national sample, fenestrated endovascular repair has been performed with a high degree of technical and clinical success. Late survival and target vessel patency are satisfactory. These results support continued use and evaluation of this technique for juxtarenal aneurysms, but illustrate the need for a more robust evidence base.

KW - fenestrated endovascular aneurysm repair

KW - juxtarenal aneurysm

KW - target vessel

KW - endovascular aneurysm repair

KW - fenestration

KW - THORACOABDOMINAL ANEURYSMS

KW - REPORTING STANDARDS

KW - STENT

KW - COLLABORATORS

KW - EXPERIENCE

U2 - 10.1161/CIRCULATIONAHA.111.070334

DO - 10.1161/CIRCULATIONAHA.111.070334

M3 - Article

SN - 0009-7322

VL - 125

SP - 2707

EP - 2715

JO - Circulation (Baltimore)

JF - Circulation (Baltimore)

IS - 22

ER -

Early Results of Fenestrated Endovascular Repair of Juxtarenal Aortic Aneurysms in the United Kingdom

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Keywords

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