Effect of soft laser and bioactive glass on bone regeneration in the treatment of bone defects (an experimental study)

Nayer S. AboElsaad; Mena Soory; Laila M. A. Gadalla; Laila I. Ragab; Stephen Dunne; Khaled R. Zalata; Chris Louca

doi:10.1007/s10103-008-0590-y

Effect of soft laser and bioactive glass on bone regeneration in the treatment of bone defects (an experimental study)

Nayer S. AboElsaad, Mena Soory, Laila M. A. Gadalla, Laila I. Ragab, Stephen Dunne, Khaled R. Zalata, Chris Louca

Research output: Contribution to journal › Article › peer-review

26 Citations (Scopus)

Abstract

This study aimed to investigate the influence of low-power gallium-aluminium-arsenide (GaAlAs) laser [830 nm, continuous wave (CW), 40 mW and fluence 4 J/cm(2)] on the healing of surgically created bone defects in rats treated with bioactive glass graft material. Surgical bone defects were created in the mandibles of 36 Wistar rats divided into two groups, each consisting of 18 rats. Group I was treated with bioactive glass plus laser irradiation. Group II was treated with graft material only. The animals were killed at 4 weeks, 8 weeks and 12 weeks postoperatively for histological examination. Laser irradiation had significantly accelerated bone healing at 4 weeks and 8 weeks in comparison with that at the sites not irradiated. However at 12 weeks, complete healing of the defects had occurred with no difference detected. Our results have confirmed the positive effect of soft laser in accelerating bone regeneration.

Original language	English
Pages (from-to)	527 - 533
Number of pages	7
Journal	LASERS IN MEDICAL SCIENCE
Volume	24
Issue number	4
DOIs	https://doi.org/10.1007/s10103-008-0590-y
Publication status	Published - Jul 2009

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title = "Effect of soft laser and bioactive glass on bone regeneration in the treatment of bone defects (an experimental study)",

abstract = "This study aimed to investigate the influence of low-power gallium-aluminium-arsenide (GaAlAs) laser [830 nm, continuous wave (CW), 40 mW and fluence 4 J/cm(2)] on the healing of surgically created bone defects in rats treated with bioactive glass graft material. Surgical bone defects were created in the mandibles of 36 Wistar rats divided into two groups, each consisting of 18 rats. Group I was treated with bioactive glass plus laser irradiation. Group II was treated with graft material only. The animals were killed at 4 weeks, 8 weeks and 12 weeks postoperatively for histological examination. Laser irradiation had significantly accelerated bone healing at 4 weeks and 8 weeks in comparison with that at the sites not irradiated. However at 12 weeks, complete healing of the defects had occurred with no difference detected. Our results have confirmed the positive effect of soft laser in accelerating bone regeneration.",

author = "AboElsaad, {Nayer S.} and Mena Soory and Gadalla, {Laila M. A.} and Ragab, {Laila I.} and Stephen Dunne and Zalata, {Khaled R.} and Chris Louca",

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doi = "10.1007/s10103-008-0590-y",

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T1 - Effect of soft laser and bioactive glass on bone regeneration in the treatment of bone defects (an experimental study)

AU - AboElsaad, Nayer S.

AU - Soory, Mena

AU - Gadalla, Laila M. A.

AU - Ragab, Laila I.

AU - Dunne, Stephen

AU - Zalata, Khaled R.

AU - Louca, Chris

PY - 2009/7

Y1 - 2009/7

N2 - This study aimed to investigate the influence of low-power gallium-aluminium-arsenide (GaAlAs) laser [830 nm, continuous wave (CW), 40 mW and fluence 4 J/cm(2)] on the healing of surgically created bone defects in rats treated with bioactive glass graft material. Surgical bone defects were created in the mandibles of 36 Wistar rats divided into two groups, each consisting of 18 rats. Group I was treated with bioactive glass plus laser irradiation. Group II was treated with graft material only. The animals were killed at 4 weeks, 8 weeks and 12 weeks postoperatively for histological examination. Laser irradiation had significantly accelerated bone healing at 4 weeks and 8 weeks in comparison with that at the sites not irradiated. However at 12 weeks, complete healing of the defects had occurred with no difference detected. Our results have confirmed the positive effect of soft laser in accelerating bone regeneration.

AB - This study aimed to investigate the influence of low-power gallium-aluminium-arsenide (GaAlAs) laser [830 nm, continuous wave (CW), 40 mW and fluence 4 J/cm(2)] on the healing of surgically created bone defects in rats treated with bioactive glass graft material. Surgical bone defects were created in the mandibles of 36 Wistar rats divided into two groups, each consisting of 18 rats. Group I was treated with bioactive glass plus laser irradiation. Group II was treated with graft material only. The animals were killed at 4 weeks, 8 weeks and 12 weeks postoperatively for histological examination. Laser irradiation had significantly accelerated bone healing at 4 weeks and 8 weeks in comparison with that at the sites not irradiated. However at 12 weeks, complete healing of the defects had occurred with no difference detected. Our results have confirmed the positive effect of soft laser in accelerating bone regeneration.

U2 - 10.1007/s10103-008-0590-y

DO - 10.1007/s10103-008-0590-y

M3 - Article

VL - 24

SP - 527

EP - 533

JO - LASERS IN MEDICAL SCIENCE

JF - LASERS IN MEDICAL SCIENCE

IS - 4

ER -

Effect of soft laser and bioactive glass on bone regeneration in the treatment of bone defects (an experimental study)

Abstract

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