Abstract
The scaffold technology research utilizes biomimicry to produce efficient scaffolds that mimic the natural cell growth environment including the basement membrane for tissue engineering. Because the natural basement membrane is composed of fibrillar protein networks of nanoscale diameter, the scaffold produced should efficiently mimic the nanoscale topography at a low production cost. Electrospinning is a technique that can achieve that. This review discusses the physical and chemical characteristics of the basement membrane and its significance on cell growth and overall focuses on nanoscale biomimetic synthetic membrane scaffolds primarily generated using electrospinning and their application in drug delivery and tissue engineering.
| Original language | English |
|---|---|
| Article number | 910 |
| Journal | Applied Sciences (Switzerland) |
| Volume | 9 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 4 Mar 2019 |
Keywords
- BM
- Basement membrane
- Electrospun
- Fiber
- Nanofibers
- Scaffold