Engineering and stable production of recombinant IgE for cancer immunotherapy and AllergoOncology

Silvia Crescioli; Giulia Chiaruttini; Silvia Mele; Kristina M Ilieva; Giulia Pellizzari; Daniel I R Spencer; Richard A Gardner; Katie E Lacy; James F Spicer; Andrew N J Tutt; Gerd K Wagner; Sophia N Karagiannis

doi:10.1016/j.jaci.2017.12.986

Engineering and stable production of recombinant IgE for cancer immunotherapy and AllergoOncology

Silvia Crescioli, Giulia Chiaruttini, Silvia Mele, Kristina M Ilieva, Giulia Pellizzari, Daniel I R Spencer, Richard A Gardner, Katie E Lacy, James F Spicer, Andrew N J Tutt, Gerd K Wagner, Sophia N Karagiannis^*

^*Corresponding author for this work

Research output: Contribution to journal › Letter › peer-review

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Abstract

We developed a versatile, novel, time- and resource-effective tool for production of functional IgE at high yields that has wide application potential in basic research and clinical evaluations in allergy, cancer immunotherapy and AllergoOncology.

Original language	English
Pages (from-to)	1519-1523
Number of pages	5
Journal	Journal of Allergy and Clinical Immunology
Volume	141
Issue number	4
Early online date	19 Jan 2018
DOIs	https://doi.org/10.1016/j.jaci.2017.12.986
Publication status	Published - 1 Apr 2018

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Engineering and stable production_CRESCIOLI_Publishedonline31January2018_GOLD AAM (CC BY-NC-ND)Accepted author manuscript, 1.7 MBLicence: CC BY
Engineering and stable production_CRESCIOLI_Publishedonline31January2018_GOLD VoR (CC BY)Final published version, 1.17 MBLicence: CC BY

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Crescioli, S., Chiaruttini, G., Mele, S., Ilieva, K. M., Pellizzari, G., Spencer, D. I. R., Gardner, R. A., Lacy, K. E., Spicer, J. F., Tutt, A. N. J., Wagner, G. K., & Karagiannis, S. N. (2018). Engineering and stable production of recombinant IgE for cancer immunotherapy and AllergoOncology. Journal of Allergy and Clinical Immunology, 141(4), 1519-1523. https://doi.org/10.1016/j.jaci.2017.12.986

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title = "Engineering and stable production of recombinant IgE for cancer immunotherapy and AllergoOncology",

abstract = "We developed a versatile, novel, time- and resource-effective tool for production of functional IgE at high yields that has wide application potential in basic research and clinical evaluations in allergy, cancer immunotherapy and AllergoOncology.",

author = "Silvia Crescioli and Giulia Chiaruttini and Silvia Mele and Ilieva, {Kristina M} and Giulia Pellizzari and Spencer, {Daniel I R} and Gardner, {Richard A} and Lacy, {Katie E} and Spicer, {James F} and Tutt, {Andrew N J} and Wagner, {Gerd K} and Karagiannis, {Sophia N}",

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doi = "10.1016/j.jaci.2017.12.986",

language = "English",

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Crescioli, S , Chiaruttini, G , Mele, S , Ilieva, KM , Pellizzari, G, Spencer, DIR, Gardner, RA, Lacy, KE, Spicer, JF, Tutt, ANJ, Wagner, GK & Karagiannis, SN 2018, 'Engineering and stable production of recombinant IgE for cancer immunotherapy and AllergoOncology', Journal of Allergy and Clinical Immunology, vol. 141, no. 4, pp. 1519-1523. https://doi.org/10.1016/j.jaci.2017.12.986

TY - JOUR

T1 - Engineering and stable production of recombinant IgE for cancer immunotherapy and AllergoOncology

AU - Crescioli, Silvia

AU - Chiaruttini, Giulia

AU - Mele, Silvia

AU - Ilieva, Kristina M

AU - Pellizzari, Giulia

AU - Spencer, Daniel I R

AU - Gardner, Richard A

AU - Lacy, Katie E

AU - Spicer, James F

AU - Tutt, Andrew N J

AU - Wagner, Gerd K

AU - Karagiannis, Sophia N

PY - 2018/4/1

Y1 - 2018/4/1

N2 - We developed a versatile, novel, time- and resource-effective tool for production of functional IgE at high yields that has wide application potential in basic research and clinical evaluations in allergy, cancer immunotherapy and AllergoOncology.

AB - We developed a versatile, novel, time- and resource-effective tool for production of functional IgE at high yields that has wide application potential in basic research and clinical evaluations in allergy, cancer immunotherapy and AllergoOncology.

UR - http://www.scopus.com/inward/record.url?scp=85042179408&partnerID=8YFLogxK

U2 - 10.1016/j.jaci.2017.12.986

DO - 10.1016/j.jaci.2017.12.986

M3 - Letter

C2 - 29360527

SN - 0091-6749

VL - 141

SP - 1519

EP - 1523

JO - Journal of Allergy and Clinical Immunology

JF - Journal of Allergy and Clinical Immunology

IS - 4

ER -

Engineering and stable production of recombinant IgE for cancer immunotherapy and AllergoOncology

Abstract

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