Flow Visualization Through Locally Activated Nanodroplets and High Frame Rate Imaging

Matthieu Toulemonde; Ge Zhang; Robert J. Eckersley; Meng Xing Tang

doi:10.1109/ULTSYM.2018.8579657

Flow Visualization Through Locally Activated Nanodroplets and High Frame Rate Imaging

Matthieu Toulemonde^*, Ge Zhang, Robert J. Eckersley, Meng Xing Tang

^*Corresponding author for this work

Imperial College London

Research output: Contribution to journal › Conference paper › peer-review

8 Citations (Scopus)

Abstract

Blood flow visualization and quantification with ultrasound contrast agents using High-Frame-Rate (HFR) imaging has been investigated but the real-time feedback is limited because of the high computational cost. Nanodroplets have been investigated as an alternative to microbubble contrast agents, due to their smaller size, longer in vivo half-life, and spatial and temporal control on activation. In this work, a non-invasive flow visualization method is proposed through non-invasively "injecting" contrast agents by using locally activatinged decafluorobutane nanodroplets and HFR diverging imaging. Vortexes, residual flows or global flow patterns can be visualized thanks to the high temporal resolution and low computational complexity image processing.

Original language	English
Article number	8579657
Journal	IEEE International Ultrasonics Symposium, IUS
Volume	2018-January
DOIs	https://doi.org/10.1109/ULTSYM.2018.8579657
Publication status	Published - 1 Jan 2018
Event	2018 IEEE International Ultrasonics Symposium, IUS 2018 - Kobe, Japan Duration: 22 Oct 2018 → 25 Oct 2018

Keywords

Decafluorobutane Nanodroplets
Flow visualization
High frame rate
Local activation
Microbubble

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10.1109/ULTSYM.2018.8579657

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title = "Flow Visualization Through Locally Activated Nanodroplets and High Frame Rate Imaging",

abstract = "Blood flow visualization and quantification with ultrasound contrast agents using High-Frame-Rate (HFR) imaging has been investigated but the real-time feedback is limited because of the high computational cost. Nanodroplets have been investigated as an alternative to microbubble contrast agents, due to their smaller size, longer in vivo half-life, and spatial and temporal control on activation. In this work, a non-invasive flow visualization method is proposed through non-invasively {"}injecting{"} contrast agents by using locally activatinged decafluorobutane nanodroplets and HFR diverging imaging. Vortexes, residual flows or global flow patterns can be visualized thanks to the high temporal resolution and low computational complexity image processing.",

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AU - Toulemonde, Matthieu

AU - Zhang, Ge

AU - Eckersley, Robert J.

AU - Tang, Meng Xing

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Blood flow visualization and quantification with ultrasound contrast agents using High-Frame-Rate (HFR) imaging has been investigated but the real-time feedback is limited because of the high computational cost. Nanodroplets have been investigated as an alternative to microbubble contrast agents, due to their smaller size, longer in vivo half-life, and spatial and temporal control on activation. In this work, a non-invasive flow visualization method is proposed through non-invasively "injecting" contrast agents by using locally activatinged decafluorobutane nanodroplets and HFR diverging imaging. Vortexes, residual flows or global flow patterns can be visualized thanks to the high temporal resolution and low computational complexity image processing.

AB - Blood flow visualization and quantification with ultrasound contrast agents using High-Frame-Rate (HFR) imaging has been investigated but the real-time feedback is limited because of the high computational cost. Nanodroplets have been investigated as an alternative to microbubble contrast agents, due to their smaller size, longer in vivo half-life, and spatial and temporal control on activation. In this work, a non-invasive flow visualization method is proposed through non-invasively "injecting" contrast agents by using locally activatinged decafluorobutane nanodroplets and HFR diverging imaging. Vortexes, residual flows or global flow patterns can be visualized thanks to the high temporal resolution and low computational complexity image processing.

KW - Decafluorobutane Nanodroplets

KW - Flow visualization

KW - High frame rate

KW - Local activation

KW - Microbubble

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DO - 10.1109/ULTSYM.2018.8579657

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SN - 1948-5719

VL - 2018-January

JO - IEEE International Ultrasonics Symposium, IUS

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T2 - 2018 IEEE International Ultrasonics Symposium, IUS 2018

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ER -

Flow Visualization Through Locally Activated Nanodroplets and High Frame Rate Imaging

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Keywords

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