TY - JOUR
T1 - Generation of poly(N-vinylpyrrolidone) nanofibres using pressurised gyration
AU - Bahijja, Raimi-Abraham
AU - Mahalingam, Suntharavathanan
AU - Edirisinghe, Mohan
AU - Craig, Duncan Q M
PY - 2014/6/1
Y1 - 2014/6/1
N2 - The ability to generate nanofibres useful for biomedical applications at bench and at a larger scale is a significant manufacturing challenge. In this study, we demonstrate that it is possible to generate nanofibre meshes of poly(N-vinylpyrrolidone) (PVP) using pressurised gyration. The effects of altering polymer molecular weight and concentration on fibre morphology and size have been investigated, with identification of minimum values for both parameters for successful fibre fabrication. In addition, we note that changing the molecular weight may result in changes to the Fourier Transform Infrared (FTIR) spectra associated with changes in fibre intramolecular bond strength and arrangement. Overall the study has demonstrated that pressure gyration represents a feasible means of producing nanofibres (470-970 nm) on a scale commensurate with commercial viability and have identified key parameters that influence mesh structure.
AB - The ability to generate nanofibres useful for biomedical applications at bench and at a larger scale is a significant manufacturing challenge. In this study, we demonstrate that it is possible to generate nanofibre meshes of poly(N-vinylpyrrolidone) (PVP) using pressurised gyration. The effects of altering polymer molecular weight and concentration on fibre morphology and size have been investigated, with identification of minimum values for both parameters for successful fibre fabrication. In addition, we note that changing the molecular weight may result in changes to the Fourier Transform Infrared (FTIR) spectra associated with changes in fibre intramolecular bond strength and arrangement. Overall the study has demonstrated that pressure gyration represents a feasible means of producing nanofibres (470-970 nm) on a scale commensurate with commercial viability and have identified key parameters that influence mesh structure.
KW - Concentration
KW - Molecular weight
KW - Nanofibre
KW - Polymer
KW - Pressurised gyration
UR - http://www.scopus.com/inward/record.url?scp=84896524910&partnerID=8YFLogxK
U2 - 10.1016/j.msec.2014.02.016
DO - 10.1016/j.msec.2014.02.016
M3 - Article
C2 - 24863213
AN - SCOPUS:84896524910
SN - 0928-4931
VL - 39
SP - 168
EP - 176
JO - Materials Science and Engineering C: Materials for Biological Applications
JF - Materials Science and Engineering C: Materials for Biological Applications
IS - 1
ER -