TY - JOUR
T1 - High-intensity focused ultrasound in the treatment of breast tumours
AU - Peek, Mirjam C.L.
AU - Wu, Feng
PY - 2018/1/10
Y1 - 2018/1/10
N2 - High-intensity focused ultrasound (HIFU) is a minimally invasive technique that has been used for the treatment of both benign and malignant tumours. With HIFU, an ultrasound (US) beam propagates through soft tissue as a high-frequency pressure wave. The US beam is focused at a small target volume, and due to the energy building up at this site, the temperature rises, causing coagulative necrosis and protein denaturation within a few seconds. HIFU is capable of providing a completely non-invasive treatment without causing damage to the directly adjacent tissues. HIFU can be either guided by US or magnetic resonance imaging (MRI). Guided imaging is used to plan the treatment, detect any movement during the treatment and monitor response in real-time. This review describes the history of HIFU, the HIFU technique, available devices and gives an overview of the published literature in the treatment of benign and malignant breast tumours with HIFU.
AB - High-intensity focused ultrasound (HIFU) is a minimally invasive technique that has been used for the treatment of both benign and malignant tumours. With HIFU, an ultrasound (US) beam propagates through soft tissue as a high-frequency pressure wave. The US beam is focused at a small target volume, and due to the energy building up at this site, the temperature rises, causing coagulative necrosis and protein denaturation within a few seconds. HIFU is capable of providing a completely non-invasive treatment without causing damage to the directly adjacent tissues. HIFU can be either guided by US or magnetic resonance imaging (MRI). Guided imaging is used to plan the treatment, detect any movement during the treatment and monitor response in real-time. This review describes the history of HIFU, the HIFU technique, available devices and gives an overview of the published literature in the treatment of benign and malignant breast tumours with HIFU.
KW - breast cancer
KW - High-intensity focused ultrasound (HIFU)
UR - http://www.scopus.com/inward/record.url?scp=85041104222&partnerID=8YFLogxK
U2 - 10.3332/ecancer.2018.794
DO - 10.3332/ecancer.2018.794
M3 - Review article
AN - SCOPUS:85041104222
SN - 1754-6605
VL - 12
JO - ecancermedicalscience
JF - ecancermedicalscience
M1 - 794
ER -