High Prevalence of Orthostatic Hypotension in Mild Dementia

Hogne Sonnesyn; Dennis W. Nilsen; Arvid Rongve; Sabine Nore; Clive Ballard; Ole B. Tysnes; Dag Aarsland

doi:10.1159/000247586

High Prevalence of Orthostatic Hypotension in Mild Dementia

Hogne Sonnesyn, Dennis W. Nilsen, Arvid Rongve, Sabine Nore, Clive Ballard, Ole B. Tysnes, Dag Aarsland

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Abstract

Background/Aims: Orthostatic hypotension (OH) and QTc prolongation have potentially important prognostic and therapeutic consequences but have rarely been studied in patients with mild dementia. Methods: Patients with mild dementia were diagnosed according to consensus criteria after comprehensive standardized assessment. OH and QTc were assessed using standardized criteria. Results: OH was significantly more common in the dementia than in the control group, and systolic drop was higher in those with dementia with Lewy bodies. There were no significant differences in QTc values between dementia and control subjects. Conclusion: OH occurs even in patients with mild dementia, in particular in dementia with Lewy bodies. QTc was not prolonged in patients with mild dementia compared with normal controls. Copyright (c) 2009 S. Karger AG, Basel

Original language	English
Pages (from-to)	307 - 313
Number of pages	7
Journal	Dementia and Geriatric Cognitive Disorders
Volume	28
Issue number	4
DOIs	https://doi.org/10.1159/000247586
Publication status	Published - Nov 2009

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title = "High Prevalence of Orthostatic Hypotension in Mild Dementia",

abstract = "Background/Aims: Orthostatic hypotension (OH) and QTc prolongation have potentially important prognostic and therapeutic consequences but have rarely been studied in patients with mild dementia. Methods: Patients with mild dementia were diagnosed according to consensus criteria after comprehensive standardized assessment. OH and QTc were assessed using standardized criteria. Results: OH was significantly more common in the dementia than in the control group, and systolic drop was higher in those with dementia with Lewy bodies. There were no significant differences in QTc values between dementia and control subjects. Conclusion: OH occurs even in patients with mild dementia, in particular in dementia with Lewy bodies. QTc was not prolonged in patients with mild dementia compared with normal controls. Copyright (c) 2009 S. Karger AG, Basel",

author = "Hogne Sonnesyn and Nilsen, {Dennis W.} and Arvid Rongve and Sabine Nore and Clive Ballard and Tysnes, {Ole B.} and Dag Aarsland",

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doi = "10.1159/000247586",

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journal = "Dementia and Geriatric Cognitive Disorders",

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T1 - High Prevalence of Orthostatic Hypotension in Mild Dementia

AU - Sonnesyn, Hogne

AU - Nilsen, Dennis W.

AU - Rongve, Arvid

AU - Nore, Sabine

AU - Ballard, Clive

AU - Tysnes, Ole B.

AU - Aarsland, Dag

PY - 2009/11

Y1 - 2009/11

N2 - Background/Aims: Orthostatic hypotension (OH) and QTc prolongation have potentially important prognostic and therapeutic consequences but have rarely been studied in patients with mild dementia. Methods: Patients with mild dementia were diagnosed according to consensus criteria after comprehensive standardized assessment. OH and QTc were assessed using standardized criteria. Results: OH was significantly more common in the dementia than in the control group, and systolic drop was higher in those with dementia with Lewy bodies. There were no significant differences in QTc values between dementia and control subjects. Conclusion: OH occurs even in patients with mild dementia, in particular in dementia with Lewy bodies. QTc was not prolonged in patients with mild dementia compared with normal controls. Copyright (c) 2009 S. Karger AG, Basel

AB - Background/Aims: Orthostatic hypotension (OH) and QTc prolongation have potentially important prognostic and therapeutic consequences but have rarely been studied in patients with mild dementia. Methods: Patients with mild dementia were diagnosed according to consensus criteria after comprehensive standardized assessment. OH and QTc were assessed using standardized criteria. Results: OH was significantly more common in the dementia than in the control group, and systolic drop was higher in those with dementia with Lewy bodies. There were no significant differences in QTc values between dementia and control subjects. Conclusion: OH occurs even in patients with mild dementia, in particular in dementia with Lewy bodies. QTc was not prolonged in patients with mild dementia compared with normal controls. Copyright (c) 2009 S. Karger AG, Basel

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SP - 307

EP - 313

JO - Dementia and Geriatric Cognitive Disorders

JF - Dementia and Geriatric Cognitive Disorders

IS - 4

ER -

High Prevalence of Orthostatic Hypotension in Mild Dementia

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