TY - JOUR
T1 - Higher cough flow is associated with lower risk of pneumonia in acute stroke
AU - Kulnik, Stefan T.
AU - Birring, Surinder S.
AU - Hodsoll, John
AU - Moxham, John
AU - Rafferty, Gerrard F.
AU - Kalra, Lalit
PY - 2016/2/1
Y1 - 2016/2/1
N2 - There is little available evidence to demonstrate how cough strength mediates the risk of aspiration-related pneumonia in acute stroke. Our secondary analysis of trial data indicates that risk of pneumonia reduces with increasing peak cough flow (PCF) of voluntary cough (OR 0.994 for each 1 L/min increase in PCF, 95% CI 0.988 to 1.0, p=0.035); and to a lesser degree with increasing PCF of reflex cough (OR 0.998 for each 1 L/min increase in PCF, 95% CI 0.992 to 1.004, p=0.475). These data serve hypothesis generation. Further studies are needed to confirm these findings and validate their clinical utility.
AB - There is little available evidence to demonstrate how cough strength mediates the risk of aspiration-related pneumonia in acute stroke. Our secondary analysis of trial data indicates that risk of pneumonia reduces with increasing peak cough flow (PCF) of voluntary cough (OR 0.994 for each 1 L/min increase in PCF, 95% CI 0.988 to 1.0, p=0.035); and to a lesser degree with increasing PCF of reflex cough (OR 0.998 for each 1 L/min increase in PCF, 95% CI 0.992 to 1.004, p=0.475). These data serve hypothesis generation. Further studies are needed to confirm these findings and validate their clinical utility.
UR - http://www.scopus.com/inward/record.url?scp=84958642910&partnerID=8YFLogxK
U2 - 10.1136/thoraxjnl-2015-207810
DO - 10.1136/thoraxjnl-2015-207810
M3 - Article
AN - SCOPUS:84958642910
SN - 0040-6376
JO - Thorax
JF - Thorax
ER -