Hip arthroplasty fatality related to dabigatran induced gastrointestinal haemorrhage

A Carter; P Sarda; M George; S Corbett

doi:10.1308/003588414X13824511649779

Hip arthroplasty fatality related to dabigatran induced gastrointestinal haemorrhage

A Carter, P Sarda, M George, S Corbett

GSTT Guy's and St Thomas' NHS Foundation Trust

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

We report a fatality due to massive gastrointestinal haemorrhage in a patient receiving prophylactic dabigatran etexilate following a total hip replacement. A 79-year-old woman was commenced on dabigatran for venous thromboembolic prophylaxis following a total hip replacement. She presented again four days after surgery with haematemesis and hypotension but her coagulopathy could not be corrected, leading to her death. This case highlights the lack of reversal agent for dabigatran etexilate that resulted in this fatal complication.

Original language	English
Pages (from-to)	115E-117E
Number of pages	3
Journal	Annals of the Royal College of Surgeons of England
Volume	96
Issue number	1
DOIs	https://doi.org/10.1308/003588414X13824511649779
Publication status	Published - Jan 2014

Keywords

Aged
Antithrombins
Arthroplasty, Replacement, Hip
Benzimidazoles
Fatal Outcome
Female
Gastrointestinal Hemorrhage
Humans
Pyridines
Venous Thromboembolism

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10.1308/003588414X13824511649779

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abstract = "We report a fatality due to massive gastrointestinal haemorrhage in a patient receiving prophylactic dabigatran etexilate following a total hip replacement. A 79-year-old woman was commenced on dabigatran for venous thromboembolic prophylaxis following a total hip replacement. She presented again four days after surgery with haematemesis and hypotension but her coagulopathy could not be corrected, leading to her death. This case highlights the lack of reversal agent for dabigatran etexilate that resulted in this fatal complication.",

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T1 - Hip arthroplasty fatality related to dabigatran induced gastrointestinal haemorrhage

AU - Carter, A

AU - Sarda, P

AU - George, M

AU - Corbett, S

PY - 2014/1

Y1 - 2014/1

N2 - We report a fatality due to massive gastrointestinal haemorrhage in a patient receiving prophylactic dabigatran etexilate following a total hip replacement. A 79-year-old woman was commenced on dabigatran for venous thromboembolic prophylaxis following a total hip replacement. She presented again four days after surgery with haematemesis and hypotension but her coagulopathy could not be corrected, leading to her death. This case highlights the lack of reversal agent for dabigatran etexilate that resulted in this fatal complication.

AB - We report a fatality due to massive gastrointestinal haemorrhage in a patient receiving prophylactic dabigatran etexilate following a total hip replacement. A 79-year-old woman was commenced on dabigatran for venous thromboembolic prophylaxis following a total hip replacement. She presented again four days after surgery with haematemesis and hypotension but her coagulopathy could not be corrected, leading to her death. This case highlights the lack of reversal agent for dabigatran etexilate that resulted in this fatal complication.

KW - Aged

KW - Antithrombins

KW - Arthroplasty, Replacement, Hip

KW - Benzimidazoles

KW - Fatal Outcome

KW - Female

KW - Gastrointestinal Hemorrhage

KW - Humans

KW - Pyridines

KW - Venous Thromboembolism

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VL - 96

SP - 115E-117E

JO - Annals of the Royal College of Surgeons of England

JF - Annals of the Royal College of Surgeons of England

IS - 1

ER -

Hip arthroplasty fatality related to dabigatran induced gastrointestinal haemorrhage

Abstract

Keywords

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