Interaction Among Genes Influencing Ethanol Metabolism and Sex Is Association With Alcohol Use Disorders in a Tibet Population

Wanjun Guo; Qiang Wang; Gongga Lanzi; Ouzhu Luobu; Xiaohong Ma; Yingcheng Wang; Puo Zhen; Yulin Ji; Geng Wei; Zheng Wang; Wei Deng; Basang Zhuoma; Xiaoming Shi; Chengyin Yan; Chan He; Xiehe Liu; Yuejing Wu; Hongrong Luo; David A. Collier; David Ball; Tao Li; Xun Hu

doi:10.1002/ajmg.b.31020

Interaction Among Genes Influencing Ethanol Metabolism and Sex Is Association With Alcohol Use Disorders in a Tibet Population

Wanjun Guo, Qiang Wang, Gongga Lanzi, Ouzhu Luobu, Xiaohong Ma, Yingcheng Wang, Puo Zhen, Yulin Ji, Geng Wei, Zheng Wang, Wei Deng, Basang Zhuoma, Xiaoming Shi, Chengyin Yan, Chan He, Xiehe Liu, Yuejing Wu, Hongrong Luo, David A. Collier, David BallTao Li, Xun Hu

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Associations between alcohol use disorders and polymorphisms of genes influencing ethanol metabolism have been widely reported, but gene-gene and gene-sex interaction studies have rarely been examined. Using a set of samples collected during an epidemiological study of alcohol use disorders AUDs in a Tibetan population in China, we performed a case-control study to investigate the relationship between the functional polymorphisms of genes influencing ethanol metabolism and AUDs. The sample included 383 individuals with an AUDIT score >= 10 and 350 control subjects with the AUDIT score

Original language	English
Pages (from-to)	561 - 569
Number of pages	9
Journal	American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics
Volume	153B
Issue number	2
DOIs	https://doi.org/10.1002/ajmg.b.31020
Publication status	Published - Mar 2010

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Guo, W., Wang, Q., Lanzi, G., Luobu, O., Ma, X., Wang, Y., Zhen, P., Ji, Y., Wei, G., Wang, Z., Deng, W., Zhuoma, B., Shi, X., Yan, C., He, C., Liu, X., Wu, Y., Luo, H., Collier, D. A., ... Hu, X. (2010). Interaction Among Genes Influencing Ethanol Metabolism and Sex Is Association With Alcohol Use Disorders in a Tibet Population. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 153B(2), 561 - 569. https://doi.org/10.1002/ajmg.b.31020

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title = "Interaction Among Genes Influencing Ethanol Metabolism and Sex Is Association With Alcohol Use Disorders in a Tibet Population",

abstract = "Associations between alcohol use disorders and polymorphisms of genes influencing ethanol metabolism have been widely reported, but gene-gene and gene-sex interaction studies have rarely been examined. Using a set of samples collected during an epidemiological study of alcohol use disorders AUDs in a Tibetan population in China, we performed a case-control study to investigate the relationship between the functional polymorphisms of genes influencing ethanol metabolism and AUDs. The sample included 383 individuals with an AUDIT score >= 10 and 350 control subjects with the AUDIT score ",

author = "Wanjun Guo and Qiang Wang and Gongga Lanzi and Ouzhu Luobu and Xiaohong Ma and Yingcheng Wang and Puo Zhen and Yulin Ji and Geng Wei and Zheng Wang and Wei Deng and Basang Zhuoma and Xiaoming Shi and Chengyin Yan and Chan He and Xiehe Liu and Yuejing Wu and Hongrong Luo and Collier, {David A.} and David Ball and Tao Li and Xun Hu",

year = "2010",

month = mar,

doi = "10.1002/ajmg.b.31020",

language = "English",

volume = "153B",

pages = "561 -- 569",

journal = "American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics",

issn = "1552-485X",

publisher = "Wiley-Liss Inc.",

number = "2",

}

Guo, W, Wang, Q, Lanzi, G, Luobu, O, Ma, X, Wang, Y, Zhen, P, Ji, Y, Wei, G, Wang, Z, Deng, W, Zhuoma, B, Shi, X, Yan, C, He, C, Liu, X, Wu, Y, Luo, H, Collier, DA , Ball, D , Li, T & Hu, X 2010, 'Interaction Among Genes Influencing Ethanol Metabolism and Sex Is Association With Alcohol Use Disorders in a Tibet Population', American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, vol. 153B, no. 2, pp. 561 - 569. https://doi.org/10.1002/ajmg.b.31020

TY - JOUR

T1 - Interaction Among Genes Influencing Ethanol Metabolism and Sex Is Association With Alcohol Use Disorders in a Tibet Population

AU - Guo, Wanjun

AU - Wang, Qiang

AU - Lanzi, Gongga

AU - Luobu, Ouzhu

AU - Ma, Xiaohong

AU - Wang, Yingcheng

AU - Zhen, Puo

AU - Ji, Yulin

AU - Wei, Geng

AU - Wang, Zheng

AU - Deng, Wei

AU - Zhuoma, Basang

AU - Shi, Xiaoming

AU - Yan, Chengyin

AU - He, Chan

AU - Liu, Xiehe

AU - Wu, Yuejing

AU - Luo, Hongrong

AU - Collier, David A.

AU - Ball, David

AU - Li, Tao

AU - Hu, Xun

PY - 2010/3

Y1 - 2010/3

N2 - Associations between alcohol use disorders and polymorphisms of genes influencing ethanol metabolism have been widely reported, but gene-gene and gene-sex interaction studies have rarely been examined. Using a set of samples collected during an epidemiological study of alcohol use disorders AUDs in a Tibetan population in China, we performed a case-control study to investigate the relationship between the functional polymorphisms of genes influencing ethanol metabolism and AUDs. The sample included 383 individuals with an AUDIT score >= 10 and 350 control subjects with the AUDIT score

AB - Associations between alcohol use disorders and polymorphisms of genes influencing ethanol metabolism have been widely reported, but gene-gene and gene-sex interaction studies have rarely been examined. Using a set of samples collected during an epidemiological study of alcohol use disorders AUDs in a Tibetan population in China, we performed a case-control study to investigate the relationship between the functional polymorphisms of genes influencing ethanol metabolism and AUDs. The sample included 383 individuals with an AUDIT score >= 10 and 350 control subjects with the AUDIT score

U2 - 10.1002/ajmg.b.31020

DO - 10.1002/ajmg.b.31020

M3 - Article

SN - 1552-485X

VL - 153B

SP - 561

EP - 569

JO - American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics

JF - American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics

IS - 2

ER -

Interaction Among Genes Influencing Ethanol Metabolism and Sex Is Association With Alcohol Use Disorders in a Tibet Population

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