TY - JOUR
T1 - Investigating the nonlinear microbubble response to chirp encoded, multipulse sequences
AU - Chetty, Kevin
AU - Hajnal, Joseph V.
AU - Eckersley, Robert J.
PY - 2006/12
Y1 - 2006/12
N2 - A modified Rayleigh-Plesset model was used to investigate the nonlinear acoustic response of ultrasound contrast microbubbles to multipulse phase and amplitude modulated, chirp encoded sequences. Trade-offs between the signal-to-noise ratio (SNR) and axial resolution were quantified for differing chirp time-bandwidth products and methods for minimising the artifacts formed in the postprocessing stages were developed. It was found that the chirp length can be increased and bandwidth reduced to improve SNR, though resolution is sacrificed. Results from the simulated chirp, pulse inverted, amplitude modulated (chirp PIAM) sequences were also compared with equivalent short pulse PIAM sequences and it was found that the chirp sequences preserve their extra energy after scattering, which translates to an improved SNR after processing. Compression artifacts were reduced by using chirps with a centre frequency and bandwidth tuned to the frequency response of the microbubble and reversing the frequency sweep of one chirp in the sequence.
AB - A modified Rayleigh-Plesset model was used to investigate the nonlinear acoustic response of ultrasound contrast microbubbles to multipulse phase and amplitude modulated, chirp encoded sequences. Trade-offs between the signal-to-noise ratio (SNR) and axial resolution were quantified for differing chirp time-bandwidth products and methods for minimising the artifacts formed in the postprocessing stages were developed. It was found that the chirp length can be increased and bandwidth reduced to improve SNR, though resolution is sacrificed. Results from the simulated chirp, pulse inverted, amplitude modulated (chirp PIAM) sequences were also compared with equivalent short pulse PIAM sequences and it was found that the chirp sequences preserve their extra energy after scattering, which translates to an improved SNR after processing. Compression artifacts were reduced by using chirps with a centre frequency and bandwidth tuned to the frequency response of the microbubble and reversing the frequency sweep of one chirp in the sequence.
U2 - 10.1016/j.ultrasmedbio.2006.06.022
DO - 10.1016/j.ultrasmedbio.2006.06.022
M3 - Article
SN - 0301-5629
VL - 32
SP - 1887
EP - 1895
JO - Ultrasound in Medicine and Biology
JF - Ultrasound in Medicine and Biology
IS - 12
ER -