TY - JOUR
T1 - Is methicillin-resistant Staphylococcus aureus more virulent than methicillin-susceptible S-aureus? A comparative cohort study of British patients with nosocomial infection and bacteremia
AU - Melzer, M
AU - Eykyn, S J
AU - Gransden, W R
AU - Chinn, S
PY - 2003/12/1
Y1 - 2003/12/1
N2 - Staphylococcus aureus is the most common cause of hospital-acquired bacteremia. From 1995 through 2000, data on age, sex, patient specialty at time of first bacteremia, primary and secondary sites of infection, delay in initiating antimicrobial therapy, and patient outcome were prospectively recorded for 815 patients with nosocomial S. aureus bacteremia. The proportion of patients whose death was attributable to methicillin-resistant S. aureus (MRSA) was significantly higher than that for methicillin-susceptible S. aureus (MSSA) (11.8% vs. 5.1%; odds ratio [OR], 2.49; 95% confidence interval [CI], 1.46-4.24; P
AB - Staphylococcus aureus is the most common cause of hospital-acquired bacteremia. From 1995 through 2000, data on age, sex, patient specialty at time of first bacteremia, primary and secondary sites of infection, delay in initiating antimicrobial therapy, and patient outcome were prospectively recorded for 815 patients with nosocomial S. aureus bacteremia. The proportion of patients whose death was attributable to methicillin-resistant S. aureus (MRSA) was significantly higher than that for methicillin-susceptible S. aureus (MSSA) (11.8% vs. 5.1%; odds ratio [OR], 2.49; 95% confidence interval [CI], 1.46-4.24; P
UR - http://www.scopus.com/inward/record.url?scp=0344688312&partnerID=8YFLogxK
U2 - 10.1086/379321
DO - 10.1086/379321
M3 - Article
SN - 1537-6591
VL - 37
SP - 1453
EP - 1460
JO - Clinical Infectious Diseases
JF - Clinical Infectious Diseases
IS - 11
ER -