Lung deposition of nebulised pentamidine in children

M J O'Doherty; S H Thomas; D Gibb; C J Page; C Harrington; C Duggan; T O Nunan; N T Bateman

doi:10.1136/thx.48.3.220

Lung deposition of nebulised pentamidine in children

M J O'Doherty, S H Thomas, D Gibb, C J Page, C Harrington, C Duggan, T O Nunan, N T Bateman

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Abstract

Nebulised pentamidine is effective for preventing Pneumocystis carinii pneumonia in adults with acquired immunodeficiency syndrome. The nebuliser dose required to produce equivalent lung concentrations of pentamidine in children is unknown. This study was performed to measure pulmonary pentamidine deposition in children and to relate this to age, ventilation pattern, and body size.

Original language	English
Pages (from-to)	220-6
Number of pages	7
Journal	Thorax
Volume	48
Issue number	3
DOIs	https://doi.org/10.1136/thx.48.3.220
Publication status	Published - 1993

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title = "Lung deposition of nebulised pentamidine in children",

abstract = "Nebulised pentamidine is effective for preventing Pneumocystis carinii pneumonia in adults with acquired immunodeficiency syndrome. The nebuliser dose required to produce equivalent lung concentrations of pentamidine in children is unknown. This study was performed to measure pulmonary pentamidine deposition in children and to relate this to age, ventilation pattern, and body size.",

author = "O'Doherty, {M J} and Thomas, {S H} and D Gibb and Page, {C J} and C Harrington and C Duggan and Nunan, {T O} and Bateman, {N T}",

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T1 - Lung deposition of nebulised pentamidine in children

AU - O'Doherty, M J

AU - Thomas, S H

AU - Gibb, D

AU - Page, C J

AU - Harrington, C

AU - Duggan, C

AU - Nunan, T O

AU - Bateman, N T

PY - 1993

Y1 - 1993

N2 - Nebulised pentamidine is effective for preventing Pneumocystis carinii pneumonia in adults with acquired immunodeficiency syndrome. The nebuliser dose required to produce equivalent lung concentrations of pentamidine in children is unknown. This study was performed to measure pulmonary pentamidine deposition in children and to relate this to age, ventilation pattern, and body size.

AB - Nebulised pentamidine is effective for preventing Pneumocystis carinii pneumonia in adults with acquired immunodeficiency syndrome. The nebuliser dose required to produce equivalent lung concentrations of pentamidine in children is unknown. This study was performed to measure pulmonary pentamidine deposition in children and to relate this to age, ventilation pattern, and body size.

U2 - 10.1136/thx.48.3.220

DO - 10.1136/thx.48.3.220

M3 - Article

C2 - 8497819

SN - 0040-6376

VL - 48

SP - 220

EP - 226

JO - Thorax

JF - Thorax

IS - 3

ER -

Lung deposition of nebulised pentamidine in children

Abstract

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