Measuring Anxiety as a Treatment Endpoint in Youth with Autism Spectrum Disorder

Luc Lecavalier; Jeffrey J. Wood; Alycia K. Halladay; Nancy E. Jones; Michael G. Aman; Edwin H. Cook; Benjamin L. Handen; Bryan H. King; Deborah A. Pearson; Victoria Hallett; Katherine Anne Sullivan; Sabrina Grondhuis; Somer L. Bishop; Joseph P. Horrigan; Geraldine Dawson; Lawrence Scahill

doi:10.1007/s10803-013-1974-9

Measuring Anxiety as a Treatment Endpoint in Youth with Autism Spectrum Disorder

Luc Lecavalier, Jeffrey J. Wood, Alycia K. Halladay, Nancy E. Jones, Michael G. Aman, Edwin H. Cook, Benjamin L. Handen, Bryan H. King, Deborah A. Pearson, Victoria Hallett, Katherine Anne Sullivan, Sabrina Grondhuis, Somer L. Bishop, Joseph P. Horrigan, Geraldine Dawson, Lawrence Scahill^*

^*Corresponding author for this work

Psychology

Research output: Contribution to journal › Article › peer-review

139 Citations (Scopus)

Abstract

Despite the high rate of anxiety in individuals with autism spectrum disorder (ASD), measuring anxiety in ASD is fraught with uncertainty. This is due, in part, to incomplete consensus on the manifestations of anxiety in this population. Autism Speaks assembled a panel of experts to conduct a systematic review of available measures for anxiety in youth with ASD. To complete the review, the panel held monthly conference calls and two face-to-face meetings over a fourteen-month period. Thirty eight published studies were reviewed and ten assessment measures were examined: four were deemed appropriate for use in clinical trials, although with conditions; three were judged to be potentially appropriate, while three were considered not useful for clinical trials assessing anxiety. Despite recent advances, additional relevant, reliable and valid outcome measures are needed to evaluate treatments for anxiety in ASD.

Original language	English
Pages (from-to)	1128-1143
Number of pages	16
Journal	Journal of Autism and Developmental Disorders
Volume	44
Issue number	5
DOIs	https://doi.org/10.1007/s10803-013-1974-9
Publication status	Published - May 2014

Keywords

Autism spectrum disorder
Anxiety
Instrument
Measure
Assessment
Treatment
Intervention
PERVASIVE DEVELOPMENTAL DISORDERS
COGNITIVE-BEHAVIORAL THERAPY
DRUG-ADMINISTRATION PERSPECTIVE
MULTIPLE INFORMANT AGREEMENT
REVISED CHILD ANXIETY
CONTROLLED-TRIAL
INTERVIEW SCHEDULE
RATING-SCALE
DSM-IV
PSYCHOMETRIC PROPERTIES

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10.1007/s10803-013-1974-9

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Lecavalier, L., Wood, J. J., Halladay, A. K., Jones, N. E., Aman, M. G., Cook, E. H., Handen, B. L., King, B. H., Pearson, D. A., Hallett, V., Sullivan, K. A., Grondhuis, S., Bishop, S. L., Horrigan, J. P., Dawson, G., & Scahill, L. (2014). Measuring Anxiety as a Treatment Endpoint in Youth with Autism Spectrum Disorder. Journal of Autism and Developmental Disorders, 44(5), 1128-1143. https://doi.org/10.1007/s10803-013-1974-9

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title = "Measuring Anxiety as a Treatment Endpoint in Youth with Autism Spectrum Disorder",

abstract = "Despite the high rate of anxiety in individuals with autism spectrum disorder (ASD), measuring anxiety in ASD is fraught with uncertainty. This is due, in part, to incomplete consensus on the manifestations of anxiety in this population. Autism Speaks assembled a panel of experts to conduct a systematic review of available measures for anxiety in youth with ASD. To complete the review, the panel held monthly conference calls and two face-to-face meetings over a fourteen-month period. Thirty eight published studies were reviewed and ten assessment measures were examined: four were deemed appropriate for use in clinical trials, although with conditions; three were judged to be potentially appropriate, while three were considered not useful for clinical trials assessing anxiety. Despite recent advances, additional relevant, reliable and valid outcome measures are needed to evaluate treatments for anxiety in ASD.",

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author = "Luc Lecavalier and Wood, {Jeffrey J.} and Halladay, {Alycia K.} and Jones, {Nancy E.} and Aman, {Michael G.} and Cook, {Edwin H.} and Handen, {Benjamin L.} and King, {Bryan H.} and Pearson, {Deborah A.} and Victoria Hallett and Sullivan, {Katherine Anne} and Sabrina Grondhuis and Bishop, {Somer L.} and Horrigan, {Joseph P.} and Geraldine Dawson and Lawrence Scahill",

year = "2014",

month = may,

doi = "10.1007/s10803-013-1974-9",

language = "English",

volume = "44",

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Lecavalier, L, Wood, JJ, Halladay, AK, Jones, NE, Aman, MG, Cook, EH, Handen, BL, King, BH, Pearson, DA, Hallett, V, Sullivan, KA, Grondhuis, S, Bishop, SL, Horrigan, JP, Dawson, G & Scahill, L 2014, 'Measuring Anxiety as a Treatment Endpoint in Youth with Autism Spectrum Disorder', Journal of Autism and Developmental Disorders, vol. 44, no. 5, pp. 1128-1143. https://doi.org/10.1007/s10803-013-1974-9

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AU - Sullivan, Katherine Anne

AU - Grondhuis, Sabrina

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KW - DRUG-ADMINISTRATION PERSPECTIVE

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KW - INTERVIEW SCHEDULE

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EP - 1143

JO - Journal of Autism and Developmental Disorders

JF - Journal of Autism and Developmental Disorders

IS - 5

ER -

Measuring Anxiety as a Treatment Endpoint in Youth with Autism Spectrum Disorder

Abstract

Keywords

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