TY - JOUR
T1 - Microwave assisted green synthesis of thiazolidin-4-one derivatives
T2 - A perspective on potent antiviral and antimicrobial activities
AU - Saini, Neha
AU - Sharma, Archana
AU - Thakur, Vijay Kumar
AU - Makatsoris, Charalampos
AU - Dandia, Anshu
AU - Bhagat, Madhulika
AU - Tonk, Rajiv Kumar
AU - Sharma, Prabodh Chander
N1 - Funding Information:
The authors PCS, VKT, AD, MB would like to express their sincere thanks to Newton Bhabha Fund for providing the foundation to establish this cross-country interdisciplinary research collaboration through Researcher Links scheme.
Publisher Copyright:
© 2020 The Authors
PY - 2020/6
Y1 - 2020/6
N2 - Thiazolidin-4-one has been known as a powerful moiety present in various approved medications. Thiazolidin-4-ones are amongst the most effective and actively explored fields of current antimicrobial and antiviral chemotherapy that portray broad spectrum and potent activity. The wide range of medicinal properties of thiazolidin-4-one related drugs encourages the medicinal chemists to synthesize a significant variety of new medicinal substances. Microwave induced organic reactions earned substantial coverages in recent years due to many advantages such as ease of work, cost-effectiveness, short reaction time and excellent yield. Microwave radiations provide a substitute for traditional heating by incorporating energy to the reactions. The usage of microwave irradiation has contributed to the emergence of innovative ideas in chemistry, as energy absorption and propagation in microwave irradiation is entirely dissimilar to the traditional heating method. In synthetic chemistry, microwave heating is a rapidly growing area of research. This review cover organic synthesis of thiazolidin-4-one analogues via the use of microwave irradiation as an effective technique and the antiviral and antimicrobial action of thiazolidin-4-one based compounds.
AB - Thiazolidin-4-one has been known as a powerful moiety present in various approved medications. Thiazolidin-4-ones are amongst the most effective and actively explored fields of current antimicrobial and antiviral chemotherapy that portray broad spectrum and potent activity. The wide range of medicinal properties of thiazolidin-4-one related drugs encourages the medicinal chemists to synthesize a significant variety of new medicinal substances. Microwave induced organic reactions earned substantial coverages in recent years due to many advantages such as ease of work, cost-effectiveness, short reaction time and excellent yield. Microwave radiations provide a substitute for traditional heating by incorporating energy to the reactions. The usage of microwave irradiation has contributed to the emergence of innovative ideas in chemistry, as energy absorption and propagation in microwave irradiation is entirely dissimilar to the traditional heating method. In synthetic chemistry, microwave heating is a rapidly growing area of research. This review cover organic synthesis of thiazolidin-4-one analogues via the use of microwave irradiation as an effective technique and the antiviral and antimicrobial action of thiazolidin-4-one based compounds.
KW - Antimicrobial activity
KW - Antiviral activity
KW - Microwave-assisted organic synthesis
KW - Thiazolidin-4-one derivatives
UR - http://www.scopus.com/inward/record.url?scp=85121723740&partnerID=8YFLogxK
U2 - 10.1016/j.crgsc.2020.100021
DO - 10.1016/j.crgsc.2020.100021
M3 - Article
AN - SCOPUS:85121723740
SN - 2666-0865
VL - 3
JO - Current Research in Green and Sustainable Chemistry
JF - Current Research in Green and Sustainable Chemistry
M1 - 100021
ER -